Author Archives: admin

Oscars 2025: Payal Kapadia’s seat at the big table

A lack of budget certainly didn’t stop the filmmaker. Her big win at Cannes, along with rave reviews, special screenings and strong distributors with festival know-how have given her an edge.

In the spring of 2022, S.S. Rajamouli’s historical action drama RRR was a huge hit in India and in the global Indian diaspora market when two American distributors floated the idea of releasing it once again — to reach an audience not usually drawn to Indian films.

With great word of mouth and reviews, the film pulled more American audiences. It was quite unlike anything Americans had seen. RRR ended up winning a few critics’ association awards and a Golden Globe for the song ‘Nattu Nattu’. One day before the final Oscars voting began, the distributors, Variance Films and Potentate Films, organised a sold-out screening in the 1,647-seat Ace Hotel Theatre in Los Angeles. A couple of weeks later, ‘Nattu Nattu’ won an Oscar for Best Achievement in Music Written for Motion Pictures.

Indian films rarely make such an impact in the U.S. during the awards seasons. I have been observing this for over four decades, first as a journalism student, then an entertainment writer and the festival director of the oldest Indian film festival in North America. Unless it is a work of the magnitude of Richard Attenborough’s Gandhi — a British-Indian co-production that won eight Oscars in 1983, beating Steven Spielberg’s most loved film E.T., the Extra-Terrestrial. Danny Boyle’s Slumdog Millionaire also won eight Oscars, but unlike Gandhi it was a British production with no Indian producer attached to it.

Grand Prix sets the ball rolling

Marketing, promotion, and celebrity endorsements are often a big part of the awards campaign. In the fall of 2001, British filmmaker Roland Joffé (The Killing Fields) called a few of his friends in Hollywood — all members of the Academy of Motion Picture Arts and Sciences. Joffé had seen Ashutosh Gowarikar’s Lagaan, which was India’s entry for the Best Foreign Language Film. He had liked the film — about a farmer during the British Raj who challenges its officers to a game of cricket to get tax exemption — and wanted to make sure his friends would attend the Academy’s screening.

But in all these years I had not seen an Indian film reach American shores with a stamp of having won an award at a major film festival — not until May 2024, when Payal Kapadia’s second feature All We Imagine as Light won the Grand Prix at the 77th Cannes Film Festival. It was the first Indian film in 30 years to play in the main competition section of the festival.

Suddenly, it seemed everyone was talking about All We Imagine as Light, a Malayalam language drama on three working women and the transformative power of friendship and sisterhood. IndieWire gave it an A rating; they are usually very conservative in their reviews. And senior critic Peter Bradshaw of The Guardian gave the film a five-star rating, comparing it to Satyajit Ray’s Mahanagar and Aranyer Din Ratri.

his followed screenings at the top three fall season festivals in North America: Telluride, Toronto and New York. There were more awards, including from several American critics’ associations. And even though India did not submit All We Imagine as Light for the Academy Award for Best International Feature Film, the buzz about it remained strong.

According to filmmaker and film preservationist Shivendra Singh Dungarpur the reason for the success of All We Imagine as Light is the new film language that Kapadia has developed. “She blends fiction with documentary style of filmmaking giving her narrative an almost hypnotic quality,” he says. “You can’t tell where the fiction begins and when it is pure documentary.” Mumbai-based Kapadia worked as an assistant with Dungarpur before she joined the Film and Television Institute of India (FTII). Her journey since has been one of resilience — overcoming wrongful charges of rioting at FTII (where her scholarship was suspended), to persisting with her vision even when her films never found a local audience. Until now.

Under a Golden spotlight

One of the advantages All We Imagine as Light could have had is its European producers. “I don’t know [if there’s a specific] benefit in having a producer from a different part of the world… but if you are keen to premiere at a film festival in Europe, then European producers know the process,” says Kapadia. “Now, many Indian producers are learning about it, along with the American festival system. Look at Reema Das. She is her own producer and has always premiered her movies at top-level festivals. Her films are very local and yet the themes resonate across the world.”

Late last year, several critics and major publications — from The New York Times to Sight and Sound magazine ranked All We Imagine as Light as the number one film of the year. In its recent Instagram post, Sight and Sound described the film as “a delicate, dreamlike tale of loneliness and fellowship” and added that the film recalled works of Ray and Wong Kar-wai. One day after Christmas, Variety named Kapadia as one of the international breakouts of the year.

So, no one seemed surprised when All We Imagine as Light received two Golden Globes nominations, including one in the Best Director category. Variety wrote this reflected “Kapadia’s growing influence in world cinema”. This was the first such nomination for an Indian filmmaker for a film made in India. In 1999, Shekhar Kapur received a Best Director nomination for Elizabeth, but that was a British production.

All We Imagine as Light also received a Golden Globes nomination for Best Motion Picture – Non-English Language. The Academy of Motion Picture Arts and Sciences only accepts one international film submitted by each individual country, but the Hollywood Foreign Press Association — the body that awards the Golden Globes — accepts submissions by producers of foreign language films. And so the filmcould compete.

For a while now, commentators have said that the Golden Globes have lost their significance. But one cannot deny that Academy members and studios seriously follow the Globes — the nominations and the awards. (And since any film that runs for a week in any of the U.S.’s six metropolitan areas is eligible to be nominated for the Oscars, All We Imagine as Light is a contender.)

Kapadia attended the Globes dressed in a black silk outfit designed by Payal Khandwala and she wore earrings gifted to her by her mother, the painter Nalini Malani. She was accompanied by her two French producers, Thomas Hakim and Julien Graff, and cinematographer Ranabir Das. “It was such a huge honour to be nominated,” Kapadia shares the day after the Golden Globes ceremony. “The nominations really put our film back in people’s attention. And of course, talking to stars you have admired is always a thrill. I met Jodie Foster as well as director Walter Salles who had both seen our movie, and they liked it!”

Kapadia’s chance of winning a Globe was never definite, given the competitive field she was in, but her name has already registered in the minds of many Academy members. Meanwhile, last week, the film was longlisted in three categories for the British Academy Film Awards (BAFTA), including best director.

Celebrity support for Indian films 

The torch of All We Imagine as Light has been kept burning by the film’s two distributors, Janus Films and Sideshow. The former had two other foreign language films nominated for the Golden Globes: Vermiglio (Italy), a drama set during World War II, and Flow (Lithuania), a fantasy adventure about a solitary cat’s survival. Flow won the Globe for the Best Motion Picture, Animated.

“We are lucky to work with Janus and Sideshow who really take care of the films they distribute,” Kapadia says. “They understand this system well and make sure that the campaign effort is streamlined and specific. We don’t have a major studio funding backing this effort so it’s sheer hard work from everyone involved.” A stark contrast to money-backed films such as RRR or even a Gandhi, which had the support of a big studio for its Oscar campaign.

But in a crowded field with Hollywood and foreign language films competing for the short attention span of Academy members, celebrity support for films can be really helpful. Late last year before the Oscar shortlists were announced, Mexican filmmaker Alfonso Cuarón hosted a screening of Kiran Rao’s Laapataa Ladies in London. British film director of Indian origin Gurinder Chadha, who is a member of the Academy along with Cuarón, also attended the screening.

In mid-November, Indian-American filmmaker Mira Nair moderated a post-screening Q&A of All We Imagine as Light with Kapadia at NeueHouse, a small theatre in Manhattan with just 86 seats. The screening was organised by Janus Films and Sideshow to generate interest before the limited release of the film on November 15 in New York City. But it was also intended to start the buzz among Academy members based in the city. The NeueHouse screening was attended by a few Indian-American Academy members, including publicist Gitesh Pandya and producer Shrihari Sathe. Nair is also an influential member of the Academy.

The same evening, Netflix hosted a screening of Laapataa Ladies in New York City. At the time, the film was in consideration for the Best International Feature Film award. Kiran Rao and Aamir Khan were present as was Nair, who did a Q&A with the director and producer. Nair then rushed to moderate the NeueHouse Q&A of All We Imagine as Light. She had seen Kapadia’s film earlier.

Is another nomination likely?

These special screenings by well-known filmmakers are held throughout the awards seasons. In December, Kapadia was interviewed by director Shuchi Talati (Girls Will Be Girls) after the film’s screening at Film Forum, a prime art-house theatre in New York City. Again, the Q&A was meant to create a buzz about All We Imagine as Light as the Academy members were getting set to watch the films in consideration. The film is now in its eighth week of theatrical run at Film Forum.

And earlier at the end of October, Kapadia was in Japan for the Tokyo International Film Festival when she had an in-depth conversation with the Japanese master Hirokazu Kore-eda. (Kore-eda received a Palm d’Or at the Cannes Film Festival in 2018 for Shoplifters. The next year Shoplifters received an Academy Award nomination for the Best Foreign Language Film.)

During the conversation, Kore-eda asked Kapadia her thoughts on All We Imagine as Light not being sent to the Academy Awards. Her response was measured and diplomatic. “I think with this film, it got a lot already. I’m very satisfied with how the journey of the film has gone. And it’s been really more than I expected. So everything that comes its way, it’s like a bonus for me.”

All We Imagine as Light has had a huge success in finding distribution deals in 85 countries. And according to Zico Maitra, one of the film’s producers, it has already opened in 43 countries, including just recently in the U.K., Germany and Spain. After a limited release in India, the film is also streaming on Disney+Hotstar. Kapadia wanted her film to be seen by people across the country. Hence, the screenings took place in major cities, but also those that could be described as Tier-II cities: Guwahati, Chandigarh and Kanpur. The OTT release is a part of the extra bonus Kapadia mentioned.

Voting for the Academy Awards is on from January 8 to 12, and the nominations will be announced on January 19. While no one can predict whether All We Imagine as Light will receive any nominations, this much is clear: Kapadia and her film already have a seat at the main dinner table. She will be there even after the award season has ended.

The writer is a film festival programmer and author.

content/source: thehindu.com (headline edited)

India secures rank as third-largest start-up hub: Defence Minister

He emphasised that India has made remarkable progress towards becoming a strong, secure, and self-reliant nation by manufacturing cutting-edge defence equipment domestically and exporting to other countries.

Defence Minister Rajnath Singh on Saturday celebrated India’s success as a global start-up leader and urged the youth to align their aspirations with the nation’s journey towards becoming a developed country by 2047, under the “Viksit Bharat” initiative.

Speaking at the convocation ceremony of a university in Meerut, Uttar Pradesh, Rajnath Singh said, “India has emerged as the third-largest start-up hub, with over 100 unicorns shaping the future of innovation and entrepreneurship.”

He emphasised that India has made remarkable progress towards becoming a strong, secure, and self-reliant nation by manufacturing cutting-edge defence equipment domestically and exporting to other countries.

The “Viksit Bharat by 2047” initiative envisions India as a developed nation by the centenary of its independence in 2047.

Highlighting the importance of innovation and ideas, Singh said, “India is establishing itself as one of the strongest nations today. Our youth, armed with new confidence and energy, can represent the country on the global stage. If you have an idea, a skill set, and the determination to work hard, opportunities and resources will never be in short supply.”

Singh underscored the decisive role of young ignited minds in achieving this vision. He added that the youth’s dreams, commitment, and innovative thinking would define India’s identity on the global stage. “The strength of a nation lies in the knowledge, skills, and determination of its young minds,” he said.

Quoting the adage, “Every age has its own heroes,” Singh described the youth as the heroes of India’s future. He encouraged the students to draw strength from their optimism, which he identified as the key to finding opportunities in challenges.

The Defence Minister also urged the youth to remain connected to India’s history, culture, and values, as these provide valuable lessons during times of challenge and doubt. “When you look beyond individual achievements and work towards social betterment, you accomplish something that ensures you are remembered for a lifetime,” he said.

Paying tribute to Swami Vivekananda on the occasion of his birth anniversary, which is celebrated as National Youth Day on January 12, Singh described him as India’s first “Global Youth.” He encouraged the youth to draw inspiration from Swami Vivekananda’s teachings and vision.

source/content: newindianexpress.com (headline edited)

Genome India data out, milestone for biotech research: PM

Prime Minister Modi stated in a video message during the Genomics Data Conclave, organised by the Department of Biotechnology.

Prime Minister Narendra Modi on Thursday unveiled the genome sequencing data of 10,000 Indian nationals, describing the occasion as a significant milestone in the field of biotechnology research.

The Genome India Data, which reflects the vast genetic diversity of the country, will be accessible to researchers through managed access at the Indian Biological Data Centre (IBDC). “I am confident this will be a milestone in the field of biotechnology research,” Prime Minister Modi stated in a video message during the Genomics Data Conclave, organised by the Department of Biotechnology.

“Today, India has taken a historic step in the world of research. Five years ago the Genome India Project was approved. Despite the challenges posed by COVID-19, our scientists have completed the project. I am very happy that more than 20 research organisations have played a very important role in the research,” Modi said.

Highlighting the importance of the database, the PM said, “Now the data of the project is available in the Indian Biological Data Center. This project will prove to be a big milestone in the Department of Biotechnology Research.”

Addressing the experts and scientists, the Prime Minister underscored the importance of recognizing India’s vastness and diversity, not just in its food, language, and geography, but also in the genetic makeup of its people. He emphasized that the genetic diversity of India plays a pivotal role in the manifestation and treatment of diseases.

Pivotal role in medicine

He emphasized that the genetic diversity of India plays a pivotal role in the manifestation and treatment of diseases. With over a billion people and a multitude of ethnic groups, the genetic profile of each community is distinct, which in turn affects how diseases manifest and how they can be effectively treated.

source/content: newindianexpress.com (headline edited)

From Japan to Malawi: Meet the 27 global Indians winning Pravasi Bharatiya awards

Among the awardees is Lekh Raj Juneja, 72, who was born in Haryana’s Gharaunda and travelled to Japan four decades ago to study fermentation science. Juneja, who headed a Japanese pharmaceutical firm earlier, now helms a snack company. He is being honoured in the ‘science & technology’ category.

FROM A former pharma CEO in Japan to a Spanish politician, a medical practitioner empanelled with the Saudi royals to a businessman in Malawi — the honours for overseas Indians this year typify the range and reach of the 35.4 million diaspora.

The 27 individuals and organisations chosen for the 2025 Pravasi Bharatiya Samman Awards (PBSA), to be honoured by President Droupadi Murmu Friday, hail from 24 countries, including Malawi in East Africa, Fiji, Spain, Romania, US and the UK.

Among the awardees is Lekh Raj Juneja, 72, who was born in Haryana’s Gharaunda and travelled to Japan four decades ago to study fermentation science. Juneja, who headed a Japanese pharmaceutical firm earlier, now helms a snack company. He is being honoured in the ‘science & technology’ category.

In a recent interview to a Japanese daily, Juneja said the formula for global success was an integration of the best of Indian and Japanese working styles. “Indians are very aggressive when it comes to creating strategies and moving forward, but Japanese people are great at completing things properly,” he said.

Robert Masih Nahar, 50, to be awarded in the ‘community service’ category, is a politician from Catalonia who became a member of the Senate of Spain in 2017 – the first person of Indian origin to do so. Born in Punjab’s Gurdaspur, he got a degree in chemistry and moved to Barcelona in 2005. A few years later, he started to promote cricket in Catalonia and founded the Catalonia Cricket Club. He is known as the “godfather of local cricket” in Catalonia.

Syed Anwar Khursheed from Saudi Arabia is being honoured in the ‘medical services’ category. “As I was working in King Faisal Hospital, Taif, I had the privilege to help people… Then I moved to National Guard Hospital, Riyadh. I am the royal protocol physician there… it is a great privilege for me to work for the royal family in Saudi Arabia,” he told reporters in Bhubaneswar on Thursday.

The PBSA is the highest honour conferred on overseas Indians (Non-Resident Indians, Persons of Indian Origin or an organisation established and run by them), as part of the Pravasi Bharatiya Divas Convention. A jury headed by the Vice President finalises the names of the recipients.

source/content: indianexpress.com (headline edited)

Havildar Baldev Singh, who fought in four Indo-Pak wars and was honoured by PMs from Nehru to Modi, dies at 93

Jammu-based spokesperson for the Ministry of Defence, Lt Colonel Suneel Bartwal said he died of natural causes.

Having served as a despatch runner for the Army during the Battle of Naushera and Jhangar in 1947-48, and then going on to fight in four Indo-Pak wars, Havildar Baldev Singh (retired) became a respected war hero and received many honours. On Monday, he died in his hometown of Naushera in J&K’s Rajouri district at the age of 93.

Jammu-based spokesperson for the Ministry of Defence, Lt Colonel Suneel Bartwal said he died of natural causes.

Havildar Singh was born on September 27, 1931, in the village of Naunihal in Naushera. At just 16 years of age, he volunteered to join the Bal Sena Force under the leadership of Brigadier Usman, who was Commander of the 50 Para Brigade and came to be known as the Lion of Naushera, during the Battle of Naushera and Jhangar in 1947-48.

The Bal Sena, a group of local boys aged 12-16, served as despatch runners for the Indian Army in critical moments of the battle. In recognition of their bravery, then Prime Minister Jawaharlal Nehru presented them with gramophones, watches, and the opportunity to join the Army.

Singh enlisted on November 14, 1950, and served for nearly three decades. His service spanned multiple wars, including the 1961, 1962, and 1965 Indo-Pak Wars, the Defence Ministry spokesperson said.

After retiring in October 1969, he was recalled during the Indo-Pak War of 1971 and served in the 11 JAT Battalion (25 Infantry Division) for an additional eight months before returning to civilian life.

Throughout his career, Singh received numerous honours for his service, including recognition by the country’s first Prime Minister Nehru and current Prime Minister Narendra Modi, among others.

The last rites were held at Naunihal village on Monday with full military honours and service protocols.

source/content: indianexpress.com (headline edited)

‘Excited to build on our commitment to making India AI-first’: Satya Nadella meets PM Modi

“Glad to know about Microsoft’s ambitious expansion and investment plans in India. It was also wonderful discussing various aspects of tech, innovation and AI in our meeting,” Narendra Modi said.

Microsoft CEO Satya Nadella Monday met Prime Minister Narendra Modi and held a discussion on various aspects of tech innovation and artificial intelligence (AI) while committing to make India an AI-first nation.

After the interaction, Nadella took to X to hail Modi’s leadership and said: “Thank you, PM Narendra Modi ji for your leadership. Excited to build on our commitment to making India AI-first and work together on our continued expansion in the country to ensure every Indian benefits from this AI platform shift.”

In a reply to Nadella’s X post, PM Modi too appreciated Microsoft’s efforts in expanding and investing in India. “It was indeed a delight to meet you, Satya Nadella! Glad to know about Microsoft’s ambitious expansion and investment plans in India. It was also wonderful discussing various aspects of tech, innovation and AI in our meeting,” Modi wrote.

source/content: indianexpress.com (headline edited)

IIT-Guwahati develops advanced nanotechnology for cholesterol, triglyceride detection

The institute claims that their researchers have focused on a technique that combines nanotechnology and molecular detection, which can further be translated into a point-of-care as device with an enhanced diagnostic precision.

Researchers at Indian Institute of Technology (IIT), Guwahati have developed an innovative approach to improve the detection of cholesterol and triglycerides by integrating Surface-Enhanced Raman Scattering (SERS) on the nanoscale objects, officials said.

The findings of the research were recently published in the noted journal –Biosensors and Bioelectronics.

According to Dipankar Bandyopadhyay, Professor at Centre for Nanotechnology and Department of Chemical Engineering, IIT-Guwahati, the work utilises bimetallic nanostructures that are 10,000 times thinner than the width of a human hair for the high-fidelity detection of the biomarkers in the human blood.

“The metabolic biomolecules like cholesterol and triglycerides play pivotal role in maintaining a harmonious cardiovascular health of a human body. The high (HDL) and low (LDL) density lipoproteins transport cholesterol to the cellular sites for various metabolic activities,” he said.

Bandyopadhyay explained an imbalance of LDL and HDL causes arterial plaque formation leading to hypertension, formation of blood clots, or ischemia.

On the other hand, triglycerides (TGA) transform into fatty acids and glycerol during digestion which in turn is packaged inside lipoproteins namely very low-density lipoprotein (VLDL), for transportation to the cells. An elevated level of triglycerides leads to atherosclerosis and coronary artery disease, pancreatitis, type 2 diabetes, or fatty liver, he said.

“Therefore, the timely detection of any abnormality and a close monitoring of cholesterol and triglyceride levels in blood is highly sought for. While traditional lipid profile tests of blood are reliable, they often require laboratory settings, are not available as a point-of-care solution, and can take time to provide results,” he said.

IIT-Guwahati claimed that their researchers have focused on a technique that combines nanotechnology and molecular detection, which can further be translated into a point-of-care as device with an enhanced diagnostic precision.

“The researchers employ SERS active bimetallic nanostructures – the silver shelled gold nanorods, which enable a plasmonic resonance hybridisation of silver and gold to produce augmented spectral resolutions as compared to pristine silver or gold nanorods.

“Subsequently, these bimetallic nanorods are linked to two different Raman active receptors and immobilised with the enzymes cholesterol oxidase and lipase for concurrent detection of different concentrations of cholesterol and triglycerides. Such innovations help in the development of a platform for the ultrafast point-of-care detection kit with a higher level of the detection sensitivity,” Bandyopadhyay said.

Except for the headline, this story has not been edited by The Telegraph Online staff and has been published from a syndicated feed.

source/content: telegraphindia.com (headline edited)


Indian-origin tech firms corner 1/5th of H1B visas issued by U.S.

Out of these, Infosys took the lead with 8,140 beneficiaries, followed by TCS (5,274), and HCL America (2,953).

Indian-origin tech companies cornered a fifth of all H1B visas issued by the U.S. with Infosys and Tata Consultancy Services leading the pack, an analysis of data from the US immigration department showed.

According to data from the U.S. Citizenship and Immigration Services, in April-September 2024 period, out of the total 1.3 lakh H1B visas issued to different employers, about 24,766 visas were issued to Indian-origin companies.

Out of these, Infosys took the lead with 8,140 beneficiaries, followed by TCS (5,274), and HCL America (2,953).

Infosys came second to only Amazon Com Services LLC, which topped with 9,265 visas.

Cognizant, which was founded in Chennai but now has headquarters in New Jersey, ranked third in the list with 6,321 visas.

The H1B visa programme allows U.S. companies to temporarily employ foreign workers in specialty occupations. Indian companies have been significant beneficiaries of this programme, particularly in the technology sector.

Major Indian IT services firms such as Tata Consultancy Services (TCS), Infosys, Wipro, and HCL Technologies have consistently ranked among the top employers for H1B visa holders. Wipro was lower down this time with 1,634 visa grants. Tech Mahindra stood close by, having been issued 1,199 visas.

While these companies continue to benefit from the programme, ongoing developments indicate a need for adaptation in response to regulatory changes and public sentiment. The future of the H1B visa will likely depend on balancing the needs of the US businesses for skilled labour with broader immigration policy reforms.

Elon Musk, a former H-1B visa holder whose company Tesla utilises this programme, has publicly supported the tech industry’s reliance on foreign workers.

In a post on X on December 28, Mr. Musk emphasised the importance of welcoming individuals from all backgrounds who contribute to the U.S. through hard work. He passionately advocated for preserving America as a land of freedom and opportunity.

Mr. Musk’s statement also received backing from President-elect Donald Trump whose first administration restricted the programme in 2020, arguing that it allows businesses to replace Americans with lower-paid foreign workers.

source/content: thehindu.com (headline edited)

INSV Tarini with two woman Navy officers begins third leg of circumnavigation

Woman Navy officers Lt Cdr Dilna K. and Lt Cdr Roopa A began the journey on October 2, 2024 from Lyttelton Port in New Zealand to Port Stanley in Falkland Islands, the longest leg of the expedition with a distance of approximately 10,400 km to cover.

Indian Naval Sailing Vessel (INSV) Tarini left Lyttelton Port in New Zealand on Saturday (January 4, 2025) morning at about 9. 30 a.m. local time for Port Stanley (Falkland Islands) in the third leg of the ongoing global circumnavigation journey by two woman Navy officers under Navika Sagar Parikrama-II.

This is the longest leg of the expedition with a distance of approximately 5,600 nm (approximately 10,400 km) to cover. This will also be the southernmost transit of Tarini at about 56 degrees South, the Navy said in a statement. “With the frontal weather systems of the Southern Ocean, Team Tarini can expect to experience challenging seas with up to 50-60 knots (90-110 kmph) winds.”

INSV Tarini had arrived in Lyttelton on December 22, completing the second leg of the double-handed circumnavigation, which is being undertaken by two Indian Navy women officers — Lt Cdr Dilna K. and Lt Cdr Roopa A.

“During the period in Lyttelton, the crew undertook repairs and maintenance of the boat with particular focus on the next leg where the vessel will cross the South Pacific, pass through the treacherous Drake Passage, and cross Cape Horn to reach Port Stanley,” the Navy said. “While in Lyttelton, the crew also interacted with the Indian community who were eager to visit the boat and query the crew about various aspects of ocean sailing.”

INSV Tarini was open to visitors at Lyttelton Port of Christchurch (LPC) on Thursday (January 2, 2025). People from different walks of life, including Victoria Henstock, the councillor of Christchurch City Council, visited the vessel and interacted with the crew.

Maori payers for the crew

Members of the Indian diaspora as well as Belfiore Bologna, Honorary Consul of Italy for the South Island of New Zealand and Sue McFarlane, Head of Christchurch Antarctic Office turned up for the Flag Off ceremony of the vessel. Traditional Maori prayers for the crew by members of the Maori community were also undertaken during the ceremony.

The expedition was flagged off from Goa on October 02, 2024 by Navy Chief Adm Dinesh K. Tripathi. After sailing across the Indian Ocean for 38 days, INSV Tarini halted at Fremantle, Australia, from November 9 to 24, and the second leg from Fremantle to Lyttelton was covered in 28 days.

The circumnavigation will cover around 23,000 nautical miles in around 240 days, across four continents through three oceans and three challenging Capes, unfolding in five legs with stopovers at four ports for replenishment and maintenance. The five legs are Goa to Fremantle, Australia; Fremantle to Lyttleton, New Zealand; Lyttleton to Port Stanley, Falkland Islands; Port Stanley to Cape Town, South Africa; and from Cape Town back to Goa.

INSV Tarini, a 56-foot sailing vessel built by Aquarius Shipyard Ltd, was inducted in the Indian Navy on February 18, 2017. The vessel has clocked more than 66,000 nautical miles (1,22,223 km) and participated in the first edition of Navika Sagar Parikrama in 2017, trans-oceanic expedition from Goa to Rio, Goa to Port Louis and other significant expeditions. Both the officers with a sailing experience of 38,000 nautical miles (70,376km) trained vigorously in the last three years.

source/content: thehindu.com (headline edited)

Researchers from the Indian Institute of Technology Guwahati and the Bose Institute Kolkata have developed an advanced injectable hydrogel for localised cancer treatment.

This innovative hydrogel-based therapy delivers anti-cancer drugs directly to tumour sites, reducing side effects associated with cancer treatments.

Researchers from the Indian Institute of Technology Guwahati and the Bose Institute Kolkata have developed an advanced injectable hydrogel for localised cancer treatment.

This innovative hydrogel-based therapy delivers anti-cancer drugs directly to tumour sites, significantly reducing side effects typically associated with conventional cancer treatments.

The findings have been published in the “Materials Horizons”, a journal of the Royal Society of Chemistry. The paper is co-authored by Prof Debapratim Das, along with research scholars Tanushree Das and Ritvika Kushwaha from IIT Guwahati. The collaborators are Dr Kuldip Jana, Satyajit Halder and Anup Kumar Misra from the Bose Institute Kolkata.

“Cancer continues to be a pressing global health challenge, with millions of patients affected worldwide. Current treatments, such as chemotherapy and surgical interventions, often have severe limitations. Surgical removal of tumors is sometimes not feasible, particularly for internal organs, while chemotherapy’s systemic delivery often results in harmful side effects by affecting both cancerous and healthy cells,” the IIT Guwahati said in a statement.

Prof Das from the Department of Chemistry and his team addressed these challenges by designing a hydrogel that delivers drugs precisely to the tumour site, ensuring localised action.

Hydrogels are water-based, three-dimensional polymer networks capable of absorbing and retaining fluids. Their unique structure mimics living tissues, making them suitable for biomedical applications. This newly developed hydrogel acts as a stable reservoir for anti-cancer drugs and releases them in a controlled manner, responding to specific conditions in the tumour microenvironment.

The hydrogel, composed of ultra-short peptides – biocompatible and biodegradable building blocks of proteins – is designed to remain insoluble in biological fluids, ensuring it stays localized at the injection site. It responds to elevated glutathione (GSH) levels, a molecule abundant in tumour cells. Upon encountering high GSH levels, the hydrogel triggers a controlled drug release directly into the tumour, minimizing its interaction with healthy tissues and reducing systemic side effects.

Speaking about the breakthrough, Prof Das said, “This work exemplifies how scientific innovation can directly address the pressing needs of cancer treatment. The hydrogel’s unique properties allow it to work in harmony with the biological environment, offering precision where it is needed most. We are excited by its potential to transform our thoughts about localized drug delivery.”

In pre-clinical trials on a murine model of breast cancer, the hydrogel showcased remarkable efficacy. A single injection of the hydrogel, loaded with the chemotherapy drug doxorubicin, resulted in a 75% reduction in tumour size within 18 days. Crucially, the hydrogel remained localized at the tumour site, steadily releasing the drug over time without causing detectable side effects on other organs, the IIT Guwahati said.

“This innovative delivery system enhances the drug’s effectiveness while reducing the required dosage, thus minimizing toxicity. Laboratory studies further demonstrated that the hydrogel improves drug uptake by cancer cells, induces cell cycle arrest, and promotes programmed cell death, thereby attacking tumours on multiple fronts,” the institute further stated.

source/content: newindianexpress.com (headline edited)