Category Archives: Business & Economy

NATIONAL: HEALTH & MEDICAL SERVICES / INNOVATION: Indian Institute of Science (IISc) Scientists Develop Gold-Coated Vesicles to Fight Tuberculosis (TB)

The spherical vesicles, which can be delivered to immune cells, are expected to potentially trigger an immune response.

To combat tuberculosis, researchers at the Indian Institute of Science (IISc) have designed a new method under which a vaccine candidate for the disease can be delivered by making use of Outer Membrane Vesicles (OMVs). These spherical vesicles, which can be delivered to immune cells, are secreted by bacteria coated on gold nanoparticles. The deliverance is expected to potentially trigger an immune response to offer protection against TB.

Across the world, TB, which is caused by a bacterium called Mycobacterium tuberculosis, claims the lives of over a million people every year. Currently, BCG is the only effective vaccine against TB. It contains a weakened form of the disease-causing bacterium, which when injected into the bloodstream, produces antibodies which can help fight the disease.

However, the scientists have said that the BCG vaccine does not protect adolescents and adults as effectively as it does children. Prompted by this, Rachit Agarwal, Assistant Professor at the Centre for BioSystems Science and Engineering (BSSE), IISc, and his group worked on developing a potential subunit vaccine candidate that contains only parts of the infectious bacterium to stimulate an immune response.

Although other scientists had developed subunit vaccines based on a handful of proteins from the disease-causing bacteria earlier, they had not been effective in the treatment. Agarwal’s group decided to take a slightly varied approach and made use of OMVs — which are spherical membrane-bound particles released by some bacteria, and contain an assortment of proteins and lipids which could induce an immune response against the pathogen.

“They’re safer compared to a live bacterium, and since they are membrane-derived, they contain all kinds of antigens,” explained Agarwal, the senior author of the paper published in  Biomaterials Advances. The researchers further explained that while subunit vaccines typically only contain a limited number of antigens — bacterial proteins that can elicit an immune response in the host, the OMVs contain a variety of antigens, which can induce a better immune response.

“Mycobacterium-derived OMVs are usually unstable and come in different sizes, making them unsuitable for vaccine applications. But the OMVs coated on gold nanoparticles (OMV-AuNPs) by the IISc team were found to be uniform in size and stable. The researchers also found that human immune cells showed a higher uptake of OMV-AuNPs (gold nanoparticles) than of OMVs or gold nanoparticles alone”, said an IISc press release. 

According to Avijit Goswami, a former postdoctoral fellow at BSSE and one of the first authors of the study, the most challenging part was the production and scaling up of OMVs as it was a complex process. “To synthesise OMV-AuNPs, the OMVs and the gold nanoparticles are forced together through a 100 nm filter. The OMVs break up in the process and encapsulate the gold nanoparticles,” explained Edna George, a former postdoctoral fellow at BSSE, and co-first author of the study.

During this study, the immune cells, which were cultured in the lab, were treated with OMVs derived from a related bacterial species which does not cause disease in humans, called as Mycobacterium smegmatis. Furthering their research, the team plans to develop gold-coated OMVs derived directly from Mycobacterium tuberculosis. They will then test the same on animal models and carry the results forward for clinical applications.

“Such efforts could open up new avenues for the development of vaccines for other bacterial diseases as well”, the release said.

source/content: thehindu.com (headline edited)

NATIONAL: SCIENCE & TECHNOLOGY / GREEN ENERGY:Nxtra to be the First Data Center Company in India to Install Low Environment Impact Fuel Cell Technology

Fuel cell technology converts chemical energy from hydrogen and other fuels into electricity through an electrochemical reaction, not combustion, thereby reducing carbon footprint.

Bharti Airtel’s subsidiary Nxtra Data Limited to deploy low environmental impact fuel cell technology at its data center in Karnataka.

It will be the first data center company in India to deploy this technology.

The hydrogen-ready fuel cell unit will supply much cleaner energy to Nxtra’s data center in the state of Karnataka and is said to reduce emissions.

The company plans to start the unit on non-combusted natural gas and then switch to 50% hydrogen. The natural gas-powered cells will be used for primary generation with utility electrical grid and generators as backup sources.

Fuel cell technology converts chemical energy from hydrogen and other fuels into electricity through an electrochemical reaction, not combustion, thereby reducing carbon footprint.

Nxtra has already invested in developing renewable energy power plants across India and aims to achieve 50% of its power requirements through renewable energy sources in the next 12 months.

The Carlyle Group-backed company offers data centres in India to leading enterprises, hyperscalers, start-ups, SMEs and governments.

source/content: thehindu.com (headline edited)

NATIONAL: TELECOM/SPACE: INFRASTRUCTURE: India gets its First High Throughput Satellite(HTS) Broadband Service Powered by ISRO Satellites and launched by Hughes Communications (HCI)

The new HTS service will extend broadband connectivity to the most remote locations.

Hughes Communications India (HCI), a satellite internet service provider launched India’s first high throughput satellite (HTS) broadband service powered by ISRO satellites on Monday

HTS is a communication satellite that provides more throughput than conventional communication satellites or Fixed Satellite Service. Higher-throughput refers to higher data processing and transfer capacity than conventional satellites, when using the same amount of orbital spectrum.

The new HTS service will extend broadband connectivity to the remotest locations, difficult to reach otherwise, and create economic opportunities to boost the local economy, said Dr. S. Somnath, Secretary, Department of Space, and Chairman, Indian Space Research Organization.

The service will support applications like Wi-Fi hotspots for community internet access, managed SD-WAN solutions, backhaul to extend mobile network reach, and satellite internet for small businesses.

It will also support the high bandwidth requirements of government organisations, financial companies, cellular operators, mining and energy companies, among other businesses, HCI said in a release.

The HTS broadband service from Hughes combines Ku-band capacity from ISRO GSAT-11 and GSAT-29 satellites with Hughes JUPITER Platform ground technology to deliver high-speed broadband.

source/content: thehindu.com (headline edited)

NATIONAL: AGRICULTURE & FOOD / DAIRY: India’s Milk Output to Jump 3-fold to 628 mn tn in 25 years: Amul MD R S Sodhi

India’s milk production is expected to jump three-fold to 628 million tonnes in the next 25 years with an average annual growth of 4.5 per cent, said R S Sodhi, Managing Director of Amul on Monday.

The country’s milk production was 210 million tonnes in 2021, according to the MD of Gujarat Cooperative Milk Marketing Federation (GCMMF), which markets dairy products under the Amul brand.

“Milk production in India is projected to grow at a CAGR of 4.5 per cent to reach 628 million tonnes in the next 25 years,” he said while giving a presentation on the outlook of the Indian dairy sector over the next 25 years.

Sodhi was speaking at the International Dairy Federation World Dairy Summit (IDF WDS) 2022, organised at India Expo Centre & Mart here on September 12.

India’s share in global production is estimated to nearly double from 23 per cent to 45 per cent now in the next 25 years.

Sodhi also mentioned that the demand is also set to increase because of the rising population.

“The demand for milk is expected to rise to 517 million tonnes in the next 25 years, leaving an export surplus of 111 million tonnes,” he added.

The GCMMF MD said that the per capita availability of milk in India will increase to 852 grams per day in the next 25 years from 428 grams per day in 2021.

Sodhi highlighted that India’s dairy sector has the most efficient supply chain in the world.

The packaging and transportation costs for supplying milk to consumers are very less compared to the global average.

source/content: newindianexpress.com (headline edited)

INTERNATIONAL: Professor Sanoli Gun from Chennai elected as the Head , ‘First President of Asia-Oceania Women in Mathematics’ (AOWM), Germany

Sanoli Gun from city’s The Institute of Mathematical Sciences will be the first president of Asia-Oceania Women in Mathematics.

The Committee for Women in Mathematics, which is a part of The International Mathematical Union, announced on its website that the Asia-Oceania Women in Mathematics (AOWM), the continental organisation for women mathematicians, has been established by an online meeting on August 1, this year.

With over 200 founding members from the continents, the organisation will have as its first president Sanoli Gun, a professor of mathematics at The Institute of Mathematical Sciences, Chennai, who specialises in Number Theory. There are two vice-presidents – Melissa Tacy from University of Auckland, New Zealand, and Polly Sy from University of Philippines Diliman, Philippines – and executive committee members including women mathematicians from Korea, Indonesia, Japan, China, Kazhakstan and Iran.

Among its myriad activities, the International Mathematical Union is the body that awards the Fields Medals, the highest honour in mathematics. It is the largest organised body of mathematicians across the world.

“We have to set the tone, and generate funds to actually make all the programmes happen. We have to create a logo and a website to start with. We also have to integrate… Asia is a very diverse continent, and there is Oceania. So there’s a lot of work ahead,” Said Prof. Gun.

The goal of this committee is threefold – facilitate exchange of knowledge between all the member countries, and improve the number of women mathematicians working on their Ph.Ds in mathematics and the mathematical sciences. The second goal is to help women who have Ph.Ds, but somehow get lost in the system. “Maybe we can create some fellowships,” says Prof Gun. The third goal is to make conditions more favourable for those women in faculty positions in various institutes. This will help check the so-called ‘leaky pipeline’. “About steps specific to Asia and Oceania, we will have a better idea after our first EC meeting in September,” she said.

She also pointed out that when a young person takes up research in mathematics, the names she or he encounters are usually Ramanujan and Harishchandra, and very few are inspired. The importance of having the work of great women mathematicians thrown into prominence is therefore obvious. Prof. Gun also mentioned that her colleagues from Europe had spoken of having an exhibition that describes the phenomenal work done by women in mathematics.

Unlike in literature, there are no prizes specifically for women in mathematics. “This is one of the things we will try to get for young people,” she said.

Women in research and even in faculty positions face a lot of discrimination. “One way to tackle this is by creating more women mathematicians,” Prof. Gun said.

source/content: thehindu.com (headline edited)

INTERNATIONAL: NATIONAL: COLLABORATION in AI : Australia’s AICRAFT and Bengaluru’s VALDEL Inks MoU on AI in Aerospace

One more memorandum of understanding was inked between India and Australia to use artificial intelligence and machine learning in aerospace, on the final day of the Bengaluru Space Expo (BSX), 2022. 

The MoU was signed between Bengaluru-based aerospace company Valdel Advanced Technologies and Australian artificial intelligence company AICRAFT. The MoU, which was signed in the presence of Indian Space Research Organisation (ISRO) scientific secretary Shantanu Bhatawdekar and Australian Space Agency head Enrico Palermo, will work towards using the AI capabilities of AICRAFT to help Valdel with simulation and manufacturing capabilities through the use of advanced AI and machine learning.

“We are pleased that Australian industry has continued to explore tangible space collaboration with India over the past few days. Both parties have agreed to utilise AICRAFT’s advanced artificial intelligence and machine learning capability and products to support Valdel’s modelling, simulation and manufacturing capabilities. Valdel’s facilities will also be used to test AICRAFT’s systems and platforms,” said Sarah Kirlew, Consul General for South India, who announced the MoU on Wednesday.

On Monday, as many as six MoUs were signed between several Australian and Indian companies, including two Bengaluru-based companies. In addition to this, Australia’s Space Machines Company, an aerospace company, opened a new research and development office in Bengaluru.

source/content: newindianexpress.com (edited)

NATIONAL: SCIENCE, ENGINEERING TECHNOLOGY: DEFENCE: India Successfully Test-Fires Quick Reaction Surface-to-Air Missile

The system is now ready for induction into the Army, the DRDO said in a statement

India has successfully completed six flight-tests of the Quick Reaction Surface-to-Air Missile (QRSAM) system from the Integrated Test Range in Chandipur off the Odisha coast, as part of evaluation trials by the Army, the DRDO said on Thursday.

The flight-tests were carried out against high-speed aerial targets mimicking various types of threats to evaluate the capability of the weapon systems under different scenarios, it said.

“During these tests, all the mission objectives were met establishing pin-point accuracy of the weapon system with state-of-the-art guidance and control algorithms, including warhead chain,” the Defence Research and Development Organisation (DRDO) said in a statement.

source/content: thehindu.com (headline edited)

NATIONAL: INDIA RECORDS: PM Modi Inaugurates ‘Kartavya Path’, Unveils 28-ft-tall Netaji Bose Statue at India Gate

PM takes a walk around Kartavya Path.

Prime Minister Narendra Modi on Thursday Inaugurated the newly-christened Kartavya Path — a stretch from Rashtrapati Bhavan to India Gate, and unveiled a 28-ft-tall statue of Netaji Subhas Chandra Bose at India Gate. The PM also took a walk around the Kartavya Path.

According to the government, it symbolises a shift from erstwhile Rajpath being an icon of power to Kartavya Path being an example of public ownership and empowerment.

These steps are in line with the prime minister’s second ‘Panch Pran’ for New India in Amrit Kaal: ‘remove any trace of colonial mindset’, it said

The statue is part of the Centre’s ₹13,450-crore Central Vista project, which will have a new Parliament building, new office and residences for the Prime Minister and Vice-President and new ministry buildings. The North and South Blocks, the secretariat buildings flanking Rashtrapati Bhavan, will be converted into museums.

The black granite statue has been carved from a monolithic block of granite weighing 280 metric tonne. The block of granite picked for the statue was transported to Delhi from Telangana and the statue was carved out of it in over two months.

The traffic police made arrangements to ensure smooth vehicular movement in central Delhi where restrictions were imposed for the event. General traffic movement has been diverted from specific roads from 6 pm to 9 pm, officials said.

The New Delhi Municipal Council (NDMC) has replaced the erstwhile Rajpath signages with new signboards of ‘Kartavya Path’. On Wednesday, the NDMC had approved a proposal to rename Rajpath as ‘Kartavya Path’.

Shapoorji Pallonji and Company Limited has executed the redevelopment of the entire stretch from Vijay Chowk to India Gate. The project was tendered at ₹477 crore.

The CPWD has set up five vending zones where 40 vendors each will be allowed and two blocks near the India Gate with eight shops each. Some states have shown their interest to set up their food stalls.

The entire stretch has been revamped under the Modi government’s ambitious Central Vista redevelopment project.

In a statement, the prime minister’s office said over the years, Rajpath and adjoining areas of the Central Vista Avenue had been witnessing pressure of increasing traffic of visitors, putting stress on its infrastructure.

It lacked basic amenities like public toilets, drinking water, street furniture and adequate parking space. Further, there was inadequate signage, poor maintenance of water features and haphazard parking.

Also, a need was felt to organise the Republic Day parade and other national events in a less disruptive manner with minimal restrictions on public movement.

“The redevelopment has been done bearing these concerns in mind while also ensuring the integrity and continuity of architectural character,” the statement said.

(With inputs from PTI)

source/contents: thehindu.com (headline edited)

GLOBAL: INDIA’s GLOBAL HUMAN RESOURCES: Starbucks Taps Indian-born Laxman Narasimhan as its next CEO, Twitter erupts with memes

Starbucks on Thursday (September 1) named Indian-born Laxman Narasimhan its next Chief Executive Officer (CEO). Narasimhan currently heads the health and hygiene company Reckitt, from where he announced his departure earlier in the day. 

“Starbuck’s commitment to uplift humanity through connection and compassion has long distinguished the company, building an unrivalled, globally admired brand that has transformed the way we connect over coffee,” Narasimhan said after the announcement. 

Narasimhan is now joining the growing ranks of Indian-descent CEOs heading leading US corporate giants. The list goes…Satya Nadella of Microsoft, Sundar Pichai of Alphabet, Shantanu Narayen of Adobe, Punit Renjen of Deloitte and Raj Subramaniam of FedEx. 

With the announcement, a meme fest also erupted with people on social media platforms posting how Starbuck could become a little desi now. 

Laxman Narasimhan studied mechanical engineering at the University of Pune and then he headed west, picking up the Masters in German and International Studies from The Lauder Institute at The University of Pennsylvania and an MBA in Finance from The Wharton School of The University of Pennsylvania. 

Reports have mentioned that Narasimhan will join Starbucks in October. Although, he will take the helm in April 2023, after spending a few months learning about the company and its “Reinvention” plan. 

It is learned that the new plans include paying better wages for baristas, improving employee welfare and customer experience and re-imagining stores. 

source/content: wionews.com (headline edited)

NATIONAL RECORDS: HEALTH & MEDICAL SCIENCES / COVID-19: Bharat Biotech’s Recombinant Nasal Covid Vaccine gets Emergency Use Approval by Central Drugs Standard Control Organisation (CDSCO) for Primary Immunisation

Bharat Biotech’s recombinant nasal vaccine for COVID-19 has been approved by Central Drugs Standard Control Organisation (CDSCO) for primary immunization against COVID-19 in 18+ age group for restricted use in emergency situation, Health Minister Mansukh Mandaviya tweeted on Tuesday.

“Big Boost to India’s Fight Against COVID-19! Bharat Biotech’s ChAd36-SARS-CoV-S COVID-19 (Chimpanzee Adenovirus Vectored) recombinant nasal vaccine approved by @CDSCO_INDIA_INF for primary immunization against COVID-19 in 18+ age group for restricted use in emergency situation,” Mr. Mandaviya tweeted.

This is the first intranasal vaccine for COVID-19 in the country.

The Minister further tweeted that this step will strengthen our collective fight against the pandemic. “India has harnessed its science, research and development, and human resources in the fight against COVID-19 under PM Narendra Modi’s leadership. With the science-driven approach and Sabka Prayas, we will defeat COVID-19.’’

source/content: thehindu.com (headline edited)