Category Archives: Science & Technology

GLOBAL: SCIENCE & TECHNOLOGY / RESEARCH: Global Award ‘Ben Barres Spotlight 2022’ for RGCB Scientist, Dr. Karthika Rajeeve for Study on Pathogens. She is 1 of 12 Scientists Awarded Worldwide.

She has been working on the human pathogens  Chlamydia trachomatis. Her research focuses on how these pathogens evade the host immune system.

Dr. Karthika Rajeeve, staff scientist at the Rajiv Gandhi Centre for Biotechnology (RGCB), has been selected for the Ben Barres Spotlight Award, 2022.

The Ben Barres Spotlight Awards has been instituted by scientific journal eLife to perpetuate the memory of American neurobiologist Dr. Ben Barres, a transgender researcher who advocated equality in science.

Dr. Karthika is one of the 12 scientists from around the world chosen for the prestigious award this year. She has been working on the human pathogens  Chlamydia trachomatis. Her research focuses on how these pathogens evade the host immune system.

“The scientific community at RGCB is elated at the international recognition received by Dr. Karthika Rajeeve,” said Professor Chandrabhas Narayana, Director RGCB.

Money for equipment

Dr. Karthika said she would use the award to buy much-needed equipment to take forward her research, besides attending an international conference on Chlamydia biologists to increase the visibility of her work.

Chlamydia trachomatis (Ctr) is a neglected tropical disease and the infection remains asymptomatic as a silent epidemic. The bacteria persist over extended times within their host cell and thereby establish chronic infections.

Persistent and chronic infection can cause potentially fatal ectopic (outside the uterus) pregnancy, pelvic inflammatory disease and sterility.

Her study challenges a long-standing hypothesis and shows that interferon gamma can down regulate c-Myc, the key regulator of metabolism leading to chlamydial persistence.

source/content: thehindu.com (headline edited)

NATIONAL: DEFENCE / INDIAN NAVY: 5th Scorpène-class Submarine, the INS Vagir Delivered to Navy by Mazagon Dock Shipbuilders (MDL), Mumbai

It is scheduled to be commissioned into service in January.

The fifth Scorpène-class conventional submarine,  Vagir, was delivered to the Navy by Mazagon Dock Shipbuilders Limited (MDL) Mumbai on December 20. It is scheduled to be commissioned into service next month, a Navy official said.

“It is a matter of great pride that Vagir has completed all major trials including the weapon and sensor trials in the shortest time in comparison to the earlier submarines,” the Navy said in a statement. A notable achievement is that this is the third submarine delivered to the Navy in a span of 24 months, it added.

Vagir was launched into water on November 12, 2020 and commenced sea trials on February 1, 2022.

The sixth and last of the Scorpène-class submarines,  Vagsheer, was launched into water in April 2022 and is expected to be delivered to the Navy by end 2023.

Six Scorpene submarines are being built under Project-75 by MDL under technology transfer from Naval Group of France under a $3.75 billion deal signed in October 2005. The project is about four years behind schedule.

The first submarine INS  Kalvari was commissioned in December 2017, second submarine INS  Khanderi in September 2019, third one INS  Karanj in March 2021 and the fourth one INS  Vela joined service in November 2021.

Parallelly, the tender to build six more advanced conventional submarines under Project-75I is in the Request For Proposal (RFP) stage but has suffered delays.

With delays in submarine induction, the SSKs – 209s (German HDWs) and EKMs (Russian Kilo’s), are being put through the Medium Refit Life Certification (MRLC) process which will give them additional life of 10 to 15 years.

The Navy currently has 15 conventional and one nuclear submarine in service. It includes seven Russian Kilo class submarines, four German HDW submarines, four Scorpene class submarines and the indigenous nuclear ballistic missile submarine INS  Arihant.

The Navy has drawn up plans to install Air Independent Propulsion (AIP) modules on all Scorpene submarines as they go for their refit beginning with INS Kalvari in the next couple of years to enhance their endurance. Development of an indigenous AIP module developed by the Defence Research and Development Organisation (DRDO) is in advanced stages.

source/content: thehindu.com (headline edited)

GLOBAL: RANKING / SCHOLARLY RESEARCH: India Jumps from 7th to 3rd Global Ranking in Scientific Publications

India has jumped from 7th to 3rd global ranking in scientific publications. This was informed by the Union Minister for Science & Technology, Dr. Jitendra Singh on Sunday after a review meeting with the senior official of Department of Science & Technology in New Delhi.

Lauding the consistent efforts of India’s scientific fraternity, Dr Jitendra Singh gave all credit to an enabling milieu and freedom of working provided by Prime Minister Narendra Modi.

He said, the very fact that such quantum leaps in India’s scientific pursuits are happening only in the last few years is a testimony to the push given by PM Modi both in terms of the ease of policy as well as his personal indulgence and prioritisation.

Quoting the report of National Science Foundation (NSF)’s Science & Engineering Indicators 2022 of the United States, the Minister said India’s scholarly output has also increased from 60,555 papers in 2010 to 1,49,213 papers in 2020.

Dr Jitendra Singh also took pride that India now ranks 3rd in terms of number of PhDs in science and engineering.

He was also apprised that the number of patents granted to Indian scientists at India Patent Office (IPO) during the last three years has also increased from 2511 in 2018-19 to 4003 in 2019-20 and 5629 in 2020-21.

The National Science Foundation is an independent agency of the United States government that supports fundamental research and education in all the non-medical fields of science and engineering.

Mr Singh added that India’s research performance in science and technology has improved significantly over the past few years which is visible through a large amount of scientific knowledge in terms of research publications, development of technologies and innovations contributing to overall development.

source/content: newsonair.gov.in (headline edited)

NATIONAL: DEFENCE / INDIAN NAVY: ENGINEERING /SCIENCE & TECHNOLOGY / MADE IN INDIA: Indigenously Produced and Indigenously Designed ‘Missile Destroyer  INS Mormugao’ Commissioned into the Indian Navy

The INS Mormugao is said to be equipped state-of-the-art weapons and sensors, surface-to-surface and surface-to-air missiles besides modern surveillance radar which provides target data to weapon systems.

Remarking that the state-of-the-art warship INS Mormugao was a major example of the country’s indigenous defense production capability, Defence Minister Rajnath Singh on December 18 expressed confidence about India being able to cater to not just local but global ship-building needs as well.

Mr. Singh was speaking at Mumbai’s Mazagaon docks during the Commissioning Ceremony of the INS Mormugao, the second of four ‘Visakhapatnam’-class destroyers (also classed as P-15B stealth, guided-missile destroyers) indigenously designed by the Indian Navy’s Warship Design Bureau.

The warship, christened after the historic port city in the coastal State of Goa, was built by the Mazagon Dock Shipbuilders Limited (MDSL).

Also present on the occasion were General Anil Chauhan, Chief of Defence Staff (CDS) of the Indian Armed Forces; Navy Chief Admiral R. Hari Kumar; Goa CM Pramod Sawant along with Goa Governor Sreedharan Pillai among others.

“The commissioning of this warship is proof of excellence in India’s warship design and development. The INS Mormugao is one of India’s strongest warships and I have full confidence that it will facilitate remarkable growth in country’s maritime capability. The ship will be among one of the world’s most technologically-advanced missile carrier and is a major example of our indigenous defence production capability. There is no doubt that in the near future, we will cater to India’s ship-building needs but that of the world’s as well,” said Mr. Singh, adding that the country was en-route to attaining the objective of not only ‘Make in India’ but ‘Make for World’.

The INS Mormugao is said to be equipped state-of-the-art weapons and sensors, surface-to-surface and surface-to-air missiles besides modern surveillance radar which provides target data to weapon systems. Capable of achieving speeds of over 30 knots, the warship is said to be able to fight under nuclear, biological and chemical warfare conditions.

Noting the continuous increase for demand in military equipment owing to global security reasons, the Defence Minister said that the country had every opportunity to utilise its capabilities to the fullest and move forward towards making India “an indigenous shipbuilding hub.”

Commenting on the name of the warship and the historic importance of Mormugao, Mr. Singh said: “Even as a port, Mormugao has contributed significantly to the growth of India’s maritime trade. Even today, it is one of the oldest and largest ports in the country and will retain this special place due to the services it provides…be it Mormugao fort or Mormugao port, both are recorded with great distinction in Indian history of India,” he said, noting the 17th century Maratha campaign against the Portuguese under Chhatrapati Sambhaji (Shivaji’s son).

The INS Mormugao was launched in September 2016 and commenced her sea trials on December 19, 2021, coinciding with 60 years of Goa’s Liberation from Portuguese rule. Her commissioning on today (December) coincides with the day that ‘Operation Vijay’ was launched in 1961 to free Goa from Portuguese rule.

Navy Chief, Admiral R. Hari Kumar said the achievement was “indicative of the large strides” the country had taken in warship design and building capability over the last decade, while stating that the Navy had a tradition of naming ships after cities which created an enduring umbilical link between the two.

source/content: thehindu.com (headline edited)

NATIONAL: TRANSPORT / GREEN: Indian Railways bags 9 (nine) ‘National Energy Conservation Awards 2022’

The Kacheguda station bagged the first and the Guntakal Railway Station bagged the second award for adopting the best practices for energy conservation.

Indian Railways has won nine National Energy Conservation Awards for the year 2022, with the South Central Railway (SCR) bagging the first and second prize in railway station category.  These awards were given for the best energy management practices and presented by President Droupadi Murmu at a function held by Bureau of Energy Efficiency under the aegis of Ministry of Power. 

According to an official statement of the Ministry of Railway, the South Central Railway bagged the first and the second awards for energy conservation measures in railway station category. The Kacheguda station bagged the first and the Guntakal Railway Station bagged the second award for adopting the best practices for energy conservation.

The certificates of merit were awarded to the Kanpur Central Railway station under the Northern Central Railway, the Rajahmundry railway station and the Tenali Railway station. Under the buildings category, Ajmer workshop of North Western Railway was awarded the first prize. Certificate of merit was awarded to the Railway hospital Guntakal  (SCR), Electric Traction Training Centre, Vijayawada (SCR) and Divisional Railway Hospital, Pratapnagar (Western Railway).

source/content: newindianexpress.com (headlines edited)

GLOBAL: SCIENCE & TECHNOLOGY / MACHINE LEARNING : Rishi Rajpopat, Indian PhD student at Cambridge University solves 2,500-year-old Sanskrit puzzle making it possible, for the first time, to accurately use Panini’s so-called “language machine”.

Rishi Rajpopat solved the 2,500-year-old Sanskrit puzzle by decoding a rule taught by Panini, known as the father of linguistics.

A grammatical problem that has defeated Sanskrit scholars since the 5th Century BC has finally been solved by an Indian PhD student at the University of Cambridge, it emerged as his thesis was published on Thursday.

Rishi Rajpopat made the breakthrough by decoding a rule taught by Panini, known as the father of linguistics, and is now encapsulated in his thesis entitled ‘In Panini, We Trust: Discovering the Algorithm for Rule Conflict Resolution in the Astadhyayi’.

According to the university, leading Sanskrit experts have described Rajpopat’s discovery as “revolutionary” and it could now mean that Panini’s grammar can also be taught to computers for the first time.

“I had a eureka moment in Cambridge,” recalls Rajpopat.

“After nine months of trying to crack this problem, I was almost ready to quit, I was getting nowhere. So, I closed the books for a month and just enjoyed the summer, swimming, cycling, cooking, praying and meditating. Then, begrudgingly I went back to work, and, within minutes, as I turned the pages, these patterns started emerging, and it all started to make sense. There was a lot more work to do but I’d found the biggest part of the puzzle,” said the 27-year-old scholar.

Over the next few weeks, he was so excited that he couldn’t sleep and would spend hours in the library, including in the middle of the night, to check what he’d found and solve related problems. It would take another two and half years before he would get to the finish line.

“Panini had an extraordinary mind and he built a machine unrivalled in human history. He didn’t expect us to add new ideas to his rules. The more we fiddle with Panini’s grammar, the more it eludes us,” says Rajpopat.

The 2,500-year-old algorithm decoded by him makes it possible, for the first time, to accurately use Panini’s so-called “language machine”.

Rajpopat’s discovery makes it possible to “derive” any Sanskrit word, to construct millions of grammatically correct words, using Panini’s revered language machine, which is widely considered to be one of the greatest intellectual achievements in history.

Panini’s system – 4,000 rules detailed in his renowned work, the Astadhyayi, which is thought to have been written around 500 BC – is meant to work like a machine. Feed in the base and suffix of a word and it should turn them into grammatically correct words and sentences through a step-by-step process.

Until now, however, there has been a big problem. Often, two or more of Panini’s rules are simultaneously applicable at the same step leaving scholars to agonise over which one to choose. Solving so-called “rule conflicts”, which affect millions of Sanskrit words including certain forms of “mantra” and “guru”, requires an algorithm. Rajpopat’s research shows that Panini’s so-called language machine is also self-sufficient.

“My student Rishi has cracked it – he has found an extraordinarily elegant solution to a problem that has perplexed scholars for centuries. This discovery will revolutionise the study of Sanskrit at a time when interest in the language is on the rise,” said Professor Vincenzo Vergiani, Sanskrit professor and Rajpopat’s PhD supervisor.

Six months before Rajpopat made his discovery, Professor Vergiani gave him some prescient advice: “If the solution is complicated, you are probably wrong”. A major implication of Rajpopat’s discovery is that now there is the algorithm that runs Panini’s grammar, it could potentially teach this grammar to computers.

“Computer scientists working on Natural Language Processing gave up on rule-based approaches over 50 years ago. So teaching computers how to combine the speaker’s intention with Panini’s rule-based grammar to produce human speech would be a major milestone in the history of human interaction with machines, as well as in India’s intellectual history,” said Rajpopat.

Sanskrit is an ancient and classical Indo-European language from South Asia. While only spoken in India by an estimated 25,000 people today, it has influenced many other languages and cultures around the world.

“Some of the most ancient wisdom of India has been produced in Sanskrit and we still don’t fully understand what our ancestors achieved. We’ve often been led to believe that we’re not important, that we haven’t brought enough to the table. I hope this discovery will infuse students in India with confidence, pride, and hope that they too can achieve great things,” added Rajpopat.

source/content: thehindu.com (headline edited)

INTERNATIONAL: HEALTH & MEDICAL SCIENCES / ALTERNATIVE: 9th World Ayurveda Congress 2022: Experts pitch for Innovations and Research in Ayurveda

Anirudha Joshi said he was envisaging developing wearable devices that could provide vital information about anatomy.

Ayurveda has an enormous potential for innovation but that requires an extensive technology-based research and a concrete roadmap to make it a global brand and its products effective and successful, said experts at the 9th World Ayurveda Congress (WAC) here.

“There are great possibilities of innovations in Ayurveda. There are challenges to develop techniques more advanced than supercomputers. We will have to work on those areas of computing which have not been heard of,” Padma Bhushan Vijay Bhatkar said, while chairing a plenary session on ‘Innovation and Entrepreneurs in Ayurveda’.

Anirudha Joshi, who is credited with developing award-winning ‘Nadi Tarangini’, an Artificial Intelligence-based instrument for pulse-reading, said he was envisaging developing wearable devices that could provide vital information about the human body.

“It will be very helpful if we can develop wearables which can do ‘Astha-vidha-pariksha’. Our vision is to go into prediction of different stages of a disease so that we can defer a disease if we cannot prevent it,” he explained.

In his concluding remarks, Mr. Bhatkar said, “There is a need to develop new devices like `Nadi Tarangini’. We will have to think of ways of marketing, packaging, advertising our products and how they can be shown to the world.’‘ According to Kartikeya Baldva, CEO, Ixoreal Biomed Inc, Ayurveda, a traditional wellness system, had finally arrived but there was still a long way to go.

“It is very important to ensure the success of products but that would require quality, efficacy, branding, marketing and innovation,” he emphasised.

Ajit Kolatkar, Founder- Director of Pune- based Gastrolab India Pvt Ltd, said Ayurveda had to move in such a fashion that a doctor could diagnose the ailments of a patient by using minimum devices.

”We will have to start with fundamental research from Ayurvedic perspective. There has to be a concrete roadmap. There is a need to revisit Ayurveda in the context of contemporary science,” he said, adding there were many key areas where Ayurveda could contribute significantly.

Rishabh Chopra, founder of Ayurveda Experience, an Ayurvedic health and wellness platform, said ‘Ashwagandha’ had now become a popular product in the West.

However, there were several challenges to make Ayurvedic products globally acceptable. He also said Ashwagandha, turmeric and Yoga were some of the most online searched words in the West.

“Our vision is to go into prediction of different stages of a disease so that we can defer a disease if we cannot prevent it”Anirudha Joshi,Inventor,  ‘Nadi Tarangini’

source/content: thehindu.com (headline edited)

GLOBAL: BUSINESS LEADER : Sundar Pichai, CEO Google & Alphabet, Awarded with Padma Bhushan, says, ‘India is a part of me…’

India’s Ambassador to the US Taranjit Singh Sandhu handed over the award to Pichai.

Google and Alphabet CEO Sundar Pichai was awarded the Padma Bhushan – India’s third-highest civilian award – for 2022 in the Trade and Industry category on Friday in the presence of his close family members in San Francisco. India’s Ambassador to the US Taranjit Singh Sandhu handed over the award to Pichai and said that his “inspirational journey reaffirms Indian talent’s contribution to global innovation”.

“Delighted to hand over Padma Bhushan to Google CEO Sundar Pichai in San Francisco. His inspirational journey from Madurai to Mountain View, strengthening India-America economic and tech ties, reaffirms Indian talent’s contribution to global innovation,” Sandhu wrote on Twitter.

Upon receiving the prestigious award, Pichai in his blog said India is a part of him.

“India is a part of me and I carry it with me wherever I go. I was fortunate to grow up in a family that cherished learning and knowledge, with parents who sacrificed a lot to make sure I had opportunities to explore my interests,” he said.

Pichai added, “I am deeply grateful to the Indian government and the people of India for this immense honour. It is incredibly meaningful to be honoured in this way by the country that shaped me.”

Pichai also recalled Prime Minister Narendra Modi’s vision of technology to combine the 3s -speed, simplicity, and service.

“We recently announced that we’ll be investing USD 10 billion in India’s digital future, working to enable more affordable internet access, building products for India’s unique needs, helping businesses of all sizes in their digital transformation, and using AI to tackle big societal challenges,” the Google CEO said.

“I look forward to continuing the great partnership between Google and India, as we work together to bring the benefits of technology to more people,” Pichai added.

(With inputs from agencies)

source/content: hindustantimes.com (headline edited)

NATIONAL: HEALTH & MEDICAL SCIENCES: National Drugs Regulator Approves Mylab’s PathoDetect™ kit, making it India’s First Indigenous Tuberculosis (TB) Detection Testing Kit

TB is an infectious disease, and according to the government data, India reported 1.93 million new TB cases in 2021.

India’s national drugs regulator has approved Pune based Mylab’s test kit to detect tuberculosis (TB) , making it the first made in India test kit to be approved for TB diagnosis, the company announced on Tuesday.

The kit simultaneously detects drug resistance to the two most commonly used drugs in TB treatment— Rifampicin and Isoniazid, the company added.

TB is an infectious disease, and according to the government data, India reported 1.93 million new TB cases in 2021, making it one of the major public health concerns in the country. India currently uses imported test kits; most of them come from US and Europe.

Apart from the central drugs standard control organization (CDSCO), the kit has also received approval from the national TB expert committee and the Indian Council of Medical Research (ICMR).

“We are addressing several problems simultaneously here. First being able to speed up testing by automated systems that can do multiple tests at one time. Secondly, there is scarce trained manpower for RT-PCR testing, which India can now overcome with fully automated system which does not need highly technical person to handle samples and reagents,” said Hasmukh Rawal, managing director, Mylab.

According to people familiar with the matter, this kit is more automated that others in the market and reduces the need for high expertise to run the test. Also, the kit can be stored at Indian room temperature; thus catering to look temperature requirements.

The kit is priced around ₹650 per unit, which is almost comparable to the prices of others in the market.

“We have technology to detect TB and drug resistance in the form of genexpert that’s a cartridge based nucleic acid amplification test. But this is an expensive test in the private sector and the advantage of made-in-India kit will be its low cost. We will still have to be sure how reliable the technology is,” said Dr Vikas Maurya, director, department of Pulmonology, Fortis Healthcare.

According to the company, the kit has been approved after rigorous and large scale field trials and recommended by TB Expert Committee under the aegis of ICMR. Multicentre centre evaluation study and field feasibility testing studies were also carried out for the test kit.

Emphasizing on the important point of drug resistance, Rawal said, “There is a huge problem of resistance to drugs when it comes to TB.

Until now, India had to conduct 2 tests: one to detect TB first and to check drug resistance – that against only one drug (Rifampicin). With Mylab’s PathoDetect™ kit, in a single test – patients can know their active TB infection as well as drug resistance to 2 most common drugs – Isoniazid and Rifampacin – so that they take treatment that will actually work. This is a milestone moment in India’s TB Testing.”

The test kits have been designed to work in ambient temperatures compared to existing PCR options which need 2-8 degree cold storage. Mylab Compact device systems do not require special infrastructure for operations and feasibility studies done on mobile van in rural areas indicate them to be very robust, said the company.

sources/content: hindustantimes.com (headline edited)

INTERNATIONAL: SCIENCE & TECHNOLOGY / STEM : 3 Indian-origin Women – Dr Ana Baburamani, Neelima Kadiyala & Dr Indrani Mukherjee among Australia’s Superstars of STEM

Three Indian-origin women among 60 scientists, technologists, engineers and mathematicians have been selected as ‘Australia’s Superstars of STEM’.

Dr Ana Baburamani, Neelima Kadiyala and Dr Indrani Mukherjee will undertake a two-year program in 2023 and 2024 to step into the media spotlight as STEM experts.

“The new Superstars reflect the strong diversity of women and non-binary people in Australian science and technology,” a Science & Technology Australia (STA) press note stated.

The Superstars of STEM initiative is supported by STA, which is a peak body in science and technology, representing more than 105,000 scientists and technologists.

As a biomedical researcher, Dr Ana Baburamani seeks to piece together the complex process of brain development and the mechanisms contributing to brain injury.

She is presently a Scientific Advisor in the Department of Defence — Science and Technology Group.

In addition to her research, she supports early career researchers, making science accessible and promoting wider participation in and uptake of STEM careers.

She is a member of the Royal Society of Victoria and volunteers with BrainSTEM.

Dr Indrani Mukherjee, Deep time geologist at the University of Tasmania, says her “research questions key concepts, and explores links between early Earth evolution, the origin of complex life and formation of precious mineral deposits”.

“Geology has offered me a wonderful medium (the rock record) to travel as far as 3.5 billion years ago,” she said.

Neelima Kadiyala, an IT Program Manager with Challenger Limited, has over 15 years of experience delivering extensive transformation programs across multiple industries including Financial Services, Government, Telco and FMCG.

“I want to further extend my voluntary services for broader IT community across Australia,” Kadiyala, who came to Australia in 2003, said.

The programme, since its inception in 2017, selects 60 women and non-binary STEM experts and gives them the training, networks and experience to become experts in their fields as media commentators.

It also seeks to smash gender assumptions about who can work in science, technology, engineering and maths.

“The need to boost diversity in our science, technology, engineering and mathematics sector is urgent,” said Australia’s Minister for Industry and Science, Ed Husic.

“I just know these talented experts and communicators will play their part inspiring Australia’s young people, from all backgrounds – into science and technology,” Husic added.

source/content: daijiworld.com (headline edited)