Category Archives: Science & Technology

NATIONAL: MEDICAL RESEARCH : The Indian Council of Medical Research (ICMR) completes Clinical Trials of World’s First Injectable Male Contraceptive; study claims it’s safe

The findings of the phase-III clinical trial, which involved 303 candidates aged 25-40 years, were published in the international open-access Andrology journal last month.

The Indian Council of Medical Research (ICMR) has completed the clinical trials of the world’s first injectable male contraceptive which showed that it is safe and highly efficacious without any serious side effects.

The findings of the phase-III clinical trial, which involved 303 candidates aged 25-40 years, were published in the international open-access Andrology journal last month.

The open-labeled and non-randomized, multi-centre hospital-based phase-III clinical trials were carried out at five different centres (New Delhi, Udhampur, Ludhiana, Jaipur and Kharagpur) and coordinated by the ICMR, New Delhi.

Permission to conduct phase-III clinical trial was granted by the Drugs Controller General India (DCGI) and approved by the institutional ethical committees of the respective centres.

As part of the study, 303 healthy, sexually active and married men and their healthy and sexually active wives who came to the family planning clinic and department of urology or surgery for vasectomy or No Scalpel Vasectomy (NSV) were identified.

The men were injected with 60 mg of Reversible Inhibition of Sperm under Guidance (RISUG).

“The overall efficacy of RISUG with respect to achieving azoospermia was 97.3 per cent and based on pregnancy prevention was 99.02 per cent without any serious side effect,” the study stated.

“In the history of contraceptive development, RISUG presents the highest effectiveness compared to all other contraceptives both male and female as they were at the threshold of induction into a mass contraception program,” it said.

According to the study, with an ever-increasing world population, there is an urgent need to develop modern methods of male contraception for population control.

Even though vasectomy is quite effective as a contraceptive measure, some major limitations of this method call for the development of improved techniques.

An ideal male contraceptive approach should have minimally invasive drug delivery system with a one-time injection, long-term effectiveness with negligible side-effects and the option of reversal.

“To achieve these goals, a novel male contraceptive approach of Reversible Inhibition of Sperm under Guidance (RISUG) has been developed, which has the potential to become for mass use as once injectable and reversible male contraceptive method. Significant features of this method include localized injection and no detectable interaction with other body parts unlike the hormonal injectable contraceptives,” the study said.

source/content: newindianexpress.com (headline edited)

NATIONAL: SPACE INFORMATION / I.T. : Union Minister launches Web Portal ‘Apna Chandrayaan’ on ‘Mission Chandrayaan-3’ for School Children

Developed by NCERT under the aegis of the Department of School Education and Literacy (DoSEL), the Ministry of Education, Dharmendra Pradhan also released 10 special modules on Chandrayaan-3.

Union Education Minister Dharmendra Pradhan on Tuesday launched a web portal ‘Apna Chandrayaan’ having activity-based support material, including colouring books, online quizzes, and jigsaw puzzles for school students on Mission Chandrayaan-3.

Developed by NCERT under the aegis of the Department of School Education and Literacy (DoSEL), the Ministry of Education, Pradhan also released 10 special modules on Chandrayaan-3.

This offers a comprehensive overview of its various facets, including scientific, technological, and social aspects, as well as the emotional journey and team spirit of the scientists involved.

On the lines of the Mission Chandrayaan-3 module, the ministry plans to come up with more such modules on 14 different topics, including women empowerment, COVID-19 vaccination, India’s G20 Presidency, etc.

“Success of Chandrayaan 3 is one of the most significant achievements of the 21st century that has inspired the children of the country the most,” he said.

He suggested the development of the app of the web portal to make it more accessible in facilitating self-learning among students.

“Chandrayaan 3 has ignited confidence among students and inspired them to understand technology, which will help in developing scientific temperament among them,” Pradhan said.

He also said that Prime Minister Narendra Modi has requested Dr. Sreedhara Panicker Somanath, Chairman, of ISRO, and Secretary of the Department of Space, to take Chandrayaan 3 stories to the children of the country.

He also urged him to make science fun for the students.

“India will be the Viswa Guru sharing knowledge for the global good,” he said.

He suggested to the National Council of Educational Research and Training (NCERT) to bring out social stories that will make education accessible, affordable, and qualitative, and help in bringing gender parity.

At the occasion, Dr Somanath said India completed the Chandrayaan 3 Mission by using indigenous technologies and requested students to watch the launch of Gaganyaan on October 21.

source/content: newindianexpress.com (headline edited)

NATIONAL: AGRICULTURE / VEGETABLES : ICAR-Indian Institute of Vegetable Research (IIVR) helps Grow Multiple Vegetables in One Plant

 Imagine planting one plant and getting multiple vegetables from it for your kitchen needs.

Scientists at ICAR-Indian Institute of Vegetable Research (IIVR), Varanasi are now working on a new single plant that will yield three vegetables simultaneously- brinjal, tomato and chilli.

The new plant is yet to be named.

The scientists had earlier developed ‘Pomato’ that yields potatoes and tomatoes on a single plant and ‘Brimato’ that yields brinjal and tomatoes together.

Using the grafting technique, the scientists at ICAR-IIVR, first developed ‘Pomato’.

Under the guidance of IIVR director Dr T.K. Behera, Dr Anant Bahadur, principal scientist (vegetable) and head division of crop production at ICAR-IIVR, Varanasi is now working on developing this unique single plant to yield three veggies.

“The grafting of chilli and tomato plants has been done on the brinjal rootstock and the plant is growing well. We are quite hopeful that it will start yielding chilli, brinjal and tomatoes by the end of January 2024,” said Dr Bahadur.

He said that he would analyse the feasibility of its cultivation.

Speaking about ‘Pomato’, Dr Bahadur said, “Potato tubers were germinated. Then grafting of tomato plants was done on the germinated potato tubers. As per the need, the plant was irrigated from time to time. It grew well and bore tomatoes above ground and potatoes below the ground.”

‘Pomato’, as a single plate, yielded around three kg of tomatoes and around 1.25 kg of potatoes, he added.

Thereafter, in 2019, Dr Anant Bahadur with his team grafted both the brinjal and tomato hybrids on the Brinjal root stock tolerant to waterlogging and salinity.

In 2019, his team succeeded in getting the desired result. He said the ‘Brimato’ is capable of surviving in waterlogged conditions for four days, whereas a normal plant wilts and gets destroyed in such conditions within 24 hours.

In October, the plant was transplanted, and brinjals and tomatoes were harvested till March.

A single plant yields around 3 kg of tomatoes and 2.5 kgs of brinjals, said Dr Bahadur.

Dr Bahadur said, “The special plant, ‘Brimato’, yields tomatoes and brinjals. It can be grown in kitchen gardens, backyards and also in small fields.”

source/content: daijiworld.com (headline edited)

NATIONAL : SCIENCE & TECHNOLOGY / HEALTH & MEDICAL SERVICES: IIT Madras develops Steam-based method to Sterilise Medical Equipment

Researchers at the Indian Institute of Technology (IIT) Madras have developed a solar-thermal steam-based system that can help sterilise medical equipment in remote and rural areas, where access to electricity and water could be an issue.

The project, funded by the Department of Science and Technology, uses portable steam cylinders charged by renewable energy-based stations (like solar energy) that are placed strategically in rural areas for power generation, steam generation and other uses.

The team also designed special sterilisation chambers to utilise such portably stored steam and effectively sterilise the tools.

“A portable steam storage canister can be a great contribution by facilitating minor medical interventions in the developing world by sterilising surgical instruments and combating infections in rural areas,” said Prof. Sathyan Subbiah, Department of Mechanical Engineering, IIT Madras, in a statement.

“The portable canister is developed with multi-layer insulation, which can retain useful heat of steam, generated via solar plants for longer duration thus making it a viable option to sterilise equipment in remote areas. The steam that is produced in the solar plant or any other means can be stored in the portable canister which can be transported to remote locations to carry out the sterilisation activities,” he added.

Safe sterilisation of surgical instruments and other medical tools are important aspects in the health care sector. It involves cleaning and disinfecting the previously-used contaminated surgical tools before subsequent use. Steam sterilisation is one of the best disinfecting methods.

Currently, doctors carry with them a set of sterilised tools, which limits the number of patients they can see at the camp.

The project was demonstrated during a medical camp at IIT Madras campus on October 14, and is all set for further trials, following which it is intended to be deployed in the field.

source/content: daijiworld.com (headline edited)

NATIONAL: AMAZING INNOVATION IN AI: Indian engineering student builds AI model for real-time ASL sign language translation into English words

An Indian engineering student has developed an innovative AI model that can translate American Sign Language (ASL) into English words.

An Indian engineering student has developed an innovative AI model that can translate American Sign Language (ASL) into English words.

The model can recognize and translate six fundamental ASL signs like ‘Hello’, ‘I Love You’, ‘Thank You’, ‘Please’, ‘Yes’, and ‘No’.

The AI model, developed by Priyanjali Gupta, a student of Vellore Institute of Technology, was built using TensorFlow Object Detection API, utilizing transfer learning with the ssd_mobilenet model.

Gupta captured ASL gestures through a webcam that formed the basis for her AI model. In response to inquiries, Gupta acknowledged the complexity of building a dedicated deep learning model for sign detection. 

As part of a comment on a LinkedIn post, Gupta stated “You are absolutely right there’s a long long way to go to make a perfect model which can be implemented in real life. Hopefully this happens in our lifetime”.

Gupta’s AI model helps people communicate across barriers, providing a more accessible way to connect with the world. In her GitHub post, she has shared her project and code.

source/comments: thehindu.com (headline edited)

NATIONAL: AGRICULTURE : SCIENCE : Indian Institute of Science Education & Research (IISER) Bhopal team conducts Genome Sequencing of Indian Gooseberry Plant (Amla)

Researchers from the Indian Institute of Science Education and Research (IISER) Bhopal have for the first time unravelled the draft genome of the Indian gooseberry plant, popularly known as Amla.

Understanding the genetic composition of Amla can help us understand their origins, evolution, and how they create the biochemicals that are of medicinal value.

While Amla holds significant pharmaceutical and nutritional importance, its genetic composition has hitherto not been studied in detail.

“We analysed the genome and transcriptome of the amla plant using leaves from our campus. We employed advanced sequencing technologies, including 10x Genomics and Oxford Nanopore Technology (ONT) long-read sequencing, along with transcriptomic sequencing,” said lead researcher Dr Vineet Sharma, Associate Professor of Biological Sciences at IISER Bhopal, in a statement.

Amla is a well-known plant indigenous to South Asian countries and has been used in traditional Indian and Chinese medicine and home remedies for centuries.

The stone-fruit of the Amla tree is believed to have high Vitamin C content, in addition to being a rich source of various phytochemicals, minerals, and amino acids. Amla has been thought to be effective in treating conditions like unhealthy levels of fat, Type-2 diabetes, chronic gum diseases, symptomatic knee osteoarthritis, and more.

Apart from obtaining the draft genome structure of the Amla for the first time, the researchers also identified genes responsible for vitamin C biosynthesis and compared them with genes in other plants that bear vitamin C-rich fruits.

The team found that Amla’s exceptional antioxidant power comes from the adaptive evolution of certain genes involved in the production of antioxidants like vitamin C and flavonoids.

Amla’s abundant vitamin C content and the remarkable capacity of each tree to yield up to 100 kg of fruits make it superior to other vitamin C-rich fruits such as the West Indian cherry from Mexico and the camu camu fruit found in Brazil, Peru, Colombia, and Venezuela and makes it a perfect choice for switching from the synthetic to a natural source of Vitamin C.

According to the research team, the adaptive evolution of this plant could be one of the key reasons for its easy adaptation to various climatic zones and environmental conditions.

“The analysis of the whole genomic landscape of the Amla also helped us in understanding its evolutionary descent in comparison with 26 other plant species. It will also help in developing improved nutraceuticals, food, cosmetics, and pharmaceutical products, and for further horticultural and genomic studies,” Dr Sharma said.

The findings have been published recently in the open-access journal, Frontiers in Plant Science.

source/content: daijiworld.com (headline edited)

GLOBAL & NATIONAL: INFORMATION TECHNOLGY: Infosys Only Indian Firm in TIME Magazine’s World’s Best 100 Companies list

The list, curated by TIME and Statista, is dominated by global Big Tech companies like Microsoft, Apple, Alphabet and Meta Platforms which were the top four companies on the list.

IT major Infosys is the only Indian company featured in TIME Magazine’s top 100 ‘World’s Best Companies 2023’ list, dominated by Big Tech.

The Bengaluru-based professional services firm has been ranked 64th spot in the top 100 list.

“Infosys has been featured in TIME World’s Best Companies 2023 list. We are among the top 3 global professional services firms and the only brand from India in the Top 100 global rankings,” the company said in a post on X (formerly Twitter).

The list, curated by TIME and Statista, is dominated by global Big Tech companies like Microsoft, Apple, Alphabet (Google’s parent company) and Meta Platforms which were the top four companies on the list.

Other top companies in the coveted list are Accenture, Pfizer, American Express, BMW Group, Dell Technologies, Louis Vuitton, Delta Air Lines, Starbucks, Volkswagen Group, General Motors, Ford and others.

The list is based on a formula of revenue growth, employee-satisfaction surveys, and rigorous environmental, social, and corporate governance (ESG, or sustainability) data. Big Tech had a tough year, laying off tens of thousands of workers since January.

But the world’s biggest tech companies are also the ones doing best for investors, employees, and the planet.

“Microsoft, for example, the top company in the global rankings, made $72 billion in its most recent fiscal year, a 63 per cent increase from 2020, while also reducing overall emissions by 0.5 per cent,” said TIME.

Accenture, based in Dublin, had the highest ESG ranking of any company on the list.

“The rankings show just who dominates the world economic order, with fast-moving tech and business-services companies unseating the manufacturers and consumer-goods companies that once drove the global economy,” the magazine said.

source/content: newindianexpress.com (headline edited)

NATIONAL: 15 September – National Engineers Day: The Story of M Visvesvaraya, India’s Pioneering Civil Engineer

Having played a role in major public works projects across the nation, he later served as the 19th Dewan of Mysore and wrote two books on the Indian economy. Here is a look at his life and his legacy.

September 15 is marked as the birthday of Sir Mokshagundam Visvesvaraya (1861-1962), credited for his role as a civil engineer and administrator in colonial India.

Born on September 15, 1861, in the Muddenahalli village of Karnataka, ​​Visvesvaraya completed his school education in his hometown and later on went to study Bachelor of Arts at the University of Madras. He then pursued a diploma in civil engineering at the College of Science in Pune. Having played a role in major public works projects across the nation, he later served as the 19th Dewan of Mysore and wrote two books on the Indian economy. Here is a look at his life and his legacy.

After completing his engineering from the Poona College of Science, Visvesvaraya accepted an offer to work as an Assistant Engineer in the Public Works Department (PWD) of the Government of Bombay. He was 22 at the time and one of his first projects was to construct a pipe syphon across one of Panjra river’s channels. On November 15, 1909, he joined the Mysore service as Chief Engineer, ultimately assuming the position of the 19th Dewan of Mysore.

However, he took voluntary retirement in 1918 because he did not agree with the proposal to set aside state jobs for the “non-brahmin” community. After his retirement, he presided as chairman or became a member of various committees including the Bombay Technical and Industrial Education Committee, Bombay University Committee for Promoting Chemical Industries and the Cauvery Canal Committee.

M Visvesvaraya’s significant works

Some of his significant works include the introduction of the block system of irrigation in the Deccan canals in 1899, solving the problem of the “muddy and discoloured” water in the city of Sukkur located on the banks of the Indus river and inventing automatic gates meant to regulate the flow of water in reservoirs, which is patented.

According to Vigyan Prasar, “The objective of the Block System of Irrigation was ‘to distribute the benefits of an irrigation work over a large number of villages and to concentrate the irrigation in each village within blocks of specified limits and in selected soils and situations’”. The Krishnaraja Sagar Dam in Karnataka was the first to install these gates in the 1920s.

He also travelled abroad a few times and sought to understand aspects of other countries’ systems. In Italy, he studied for two months the soil erosion problem and their irrigation and drainage works. While there, he also took a trip to the sewers of Milan, accompanied by the Chief Engineer responsible for the Milan Drainage Works and asked him some particularly “large questions” which the officer was confused about, since he thought that British officers would be responsible for all such “higher work”. To this, Visvesvaraya responded that Indians’ services were appreciated and utilised if they had the necessary qualifications and worked hard.

In a speech delivered on March 16, 1912, at Central College Bangalore , Visvesvaraya said: “As compared with Europe, our climate and traditions all pre-dispose us to a life of inaction and ease. We are influenced either by religious sentiment, class patriotism or belief in kismet, whereas the activities of Western nations rest on an economic basis. While they think and act in conformity with economic necessities, we expect to prosper without acquiring the scientific precision, the inventive faculty, the thoroughness, the discipline and restraints of modern civilisation.”

On another occasion, he said: “Progress on modern lines is a necessity. We cannot afford to ignore scientific discoveries which have almost vivified material nature. Past ideals were for past times. We must adopt ourselves to the everlasting conditions of existence or be content to be left behind in the race for material prosperity.”

Visvesvaraya pleaded for a “self-examination not moral or spiritual, but secular – that is, a survey and analysis of local conditions in India and a comparative study of the same” with those in other parts of the globe.

His books, “Reconstructing India” and “Planned Economy of India” were published in 1920 and 1934, respectively.

On Education

During his three-month visit to Japan in 1898, Visvesvaraya realised that education largely determines the health of an economy. In his, “Memoirs of Working Life”, which was published in 1951, he noted that while in Japan there were some 1.5 million girls in school, there were only over 400,000 of them in Indian schools, “notwithstanding the vastly greater population in our country”.

Visvesvaraya was instrumental in the setting up of the University of Mysore in July 1916, as he was the Dewan of Mysore at the time. He believed that the aim of an educational institution should be in line with the “state of the country’s civilisation and of its material prosperity”, and that the conditions inside a university should not be very different from the ones a student has to encounter in real life.

After taking a voluntary retirement from state service in 1918, he continued work including on the Mysore Iron and Steel Works and established the Sir Jayachamarajendra Occupational Institute in Bangalore in 1943, which was later renamed Sir Jayachamarajendra Polytechnic. This institute was meant to impart special training to technicians keeping in mind the impending industrial development of India.

source/content: indianexpress.com (headline edited)

NATIONAL: DEFENCE & MANUFACTURING: New Delhi, Paris join hands to Manufacture Advanced Defence Tech

The decisions were arrived during bilateral talks between Prime Minister Narendra Modi and French President Emmanuel Macron.

India and France on Sunday decided to strengthen defence cooperation through partnerships in the design, development, testing and manufacture of advanced defence technologies and platforms, and expanding production in India.

The decisions were arrived during bilateral talks between Prime Minister Narendra Modi and French President Emmanuel Macron. 

“We discussed a series of topics and look forward to ensuring India-France relations scale new heights of progress,’’ said Modi, who had nine bilateral meetings on Sunday. The other bilateral meetings Modi had were with Canada, Germany, South Korea, Turkey, Comoros and South Korea. India and Saudi Arabia will have a bilateral meeting on Monday.

During his talks with Canadian PM Justin Trudeau, Modi raised concerns about the anti-India activities of extremist elements in Canada. The extremists are promoting secessionism and inciting violence against Indian diplomats, damaging diplomatic premises, and threatening the Indian community in Canada. Trudeau said Canada believes in freedom of expression and peaceful protests but doesn’t condone violence.

During his talks with German Chancellor Olaf Scholz, Prime Minister Modi spoke about enhancing trade, and continuous collaboration on clean energy. Turkish President Recep Tayyip Erdogan hailed India’s G20 Presidency and complimented PM Modi on the Delhi Declaration.

source/content: newindianexpress.com (headline edited)

NATIONAL: AGRICULTURE: SCIENCE & TECHNOLOGY: Prestigious M.S. Swaminathan Award for Scientist P V Satyanarayana for his Outstanding Contributions to Agriculture in 2021-22

P V Satyanarayana, principal scientist at the Agricultural Research Station, Acharya N.G. Ranga Agricultural University, Ragolu, has been awarded the prestigious M.S Swaminathan Award for his outstanding contributions to the field of agriculture during the period 2021-2022.

Satyanarayana’s pioneering work involves the development of high-yielding rice varieties that exhibit resilience against various pests and environmental challenges, including BPH, BLB, Blast, Submergence, and salinity. Additionally, he has made substantial contributions to fine-grain varieties and hybrid rice that have revolutionised agriculture across India.

P V Satyanarayana, currently serving as the Principal Scientist at the Agricultural Research Station, Acharya N.G. Ranga Agricultural University, Ragolu, boasts an impressive list of awards including the National Award as Team Leader for the Best Golden Jubilee AICIP Centre Award in 2015 and the Best Scientist Award by the Seedman Association in 2021.

This award was presented at an event at Indian Institute of Rice Research (IIRR), Hyderabad on Sunday. This biennial national award, jointly constituted by the Retired ICAR (Indian Council of Agricultural Research) Employees Association (RICAREA) and Nuziveedu Seeds Limited (NSL), includes a cash prize of Rs. 2 Lakhs and a gold medal.

Himanshu Pathak, Director General, ICAR and Secretary, Department of Agricultural Research and Education (DARE) was the chief guest at the event. Dr. R.S. Paroda, former DG, ICAR and others were present.

The award selection committee headed by Dr. A Padma Raju, Vice Chancellor of ANGRAU, recognised Dr. PV Satyanarayana for his invaluable contributions.

  1. Prabhakar Rao, Chairman and Managing Director (CMD) of Nuziveedu Seeds Limited, noted that this prestigious award has been conferred upon eight individuals to date, with four of them hailing from the Telugu-speaking states.

Referring to the ban on rice exports, he stated that if the government maintains sufficient stocks and promotes exports, it could prove advantageous for farmers. Prabhakar Rao said Nuziveedu Seeds are actively engaged in research related to high-density farming in cotton, which promises a 30-40 per cent increase in yield. With appropriate management practices, this could escalate to 50-60 per cent higher yields compared to conventional varieties.

The Retired Indian Council of Agricultural Research Employees’ Association (RICAREA) was established in 1997 with the primary mission to promote the cause of agriculture based on the ideals and objectives of the Indian Council of Agricultural Research (ICAR).

Nuziveedu Seeds Limited (NSL), operating for nearly 50 years, stands as one of India’s largest seed companies. NSL is engaged in crop improvement projects spanning over 30 crops, with breeding stations located across the country, covering a wide range of agro-climatic conditions.

source/content: daijiworld.com (headline edited)