Tag Archives: Make in India

NATIONAL: SCIENCE & HEALTH : VACCINES: Chhattisgarh scientists develop new biomarkers to predict Covid severity

The new biomarkers have been designed to diagnose early stages of infection in patients who are affected with severe COVID-19 illness.

In a major breakthrough, the scietist of the Multi-Disciplinary Research Unit (MRU) in Dr Bhimrao Ambedkar hospital, Raipur, have introduced the country’s first-ever bio marker kit that could provide early-stage severity assessment of Covid.

The research, published in Scientific Reports, a journal by the Nature Publishing Group, holds promise for enhancing patient care during the pandemic. The new biomarkers have been designed to diagnose early stages of infection in patients who are affected with severe COVID-19 illness. With the help of an invented kit, doctors will be able to decide whether it is necessary to hospitalise the patient or he can recover at home through medicines.

Under the headship of Dr Jagannath Pal, the team utilising leftover samples from routine Covid-19 tests, has developed a method with impressive accuracy-boasting a sensitivity of 91 per cent and a specificity of 94 per cent in non-comorbid.

The MRU’s research also aligns with the Prime Minister’s “Make in India” initiative. The project was supported by the health administration of Chhattisgarh and funded by the Department of Health Research (DHR), Government of India.

How the kit works

The test results determine the response of adaptive immunity to new virus infection. The test required input of leftover RNA followed by the routine COVID-19 diagnosis by RT-PCR. Complementary DNA is prepared from RNA samples by reverse transcription.

The complementary DNA is used for subsequent qPCR reactions to determine the expression of the signature genes. By analyzing the level of the genes we determine a “Severity Score”. If the score is lower than a cut-off value it indicates the good immune response (T-cell) suggesting low risk and the patient could recover without the requirement of advanced medical facility or extra drug treatments. If the score is higher than a cut-off value it indicates a poor immune response (T-cell) suggesting high risk and patients may require advanced medical facility or extra drug treatments for recovery. The same test could be used for other virus infection also.

source/content: newindianexpress.com (headline edited)

NATIONAL: HEALTH & MEDICINE: CANCER RESEARCH: President Murmu launches India’s first home-grown gene therapy for cancer -‘CAR-T cell therapy’

President Droupadi Murmu on Thursday launched India’s first home-grown gene therapy for cancer at IIT Bombay.

Describing the newly-launched treatment, named “CAR-T cell therapy,” as a beacon of hope, President Murmu expressed confidence that the therapy will provide a new lease of life to countless cancer patients.

CAR-T cell therapy, considered a groundbreaking advancement in medical science, has long been available in developed nations. However, its prohibitive costs have rendered it beyond the reach of many.

President Murmu said that the therapy is not only accessible but also the world’s most affordable CAR-T cell therapy.

She applauded the collaborative efforts between the Indian Institute of Technology, Bombay, Tata Memorial Hospital, and industry partner ImmunoACT, highlighting the indigenous therapy as an example of the ‘Make in India’ and ‘Atmanirbhar Bharat’ initiatives.

source/content: ddnews.gov.in (headline edited)

INTERNATIONAL: MANUFACTURING / AVIATION COMPONENTS: Airbus Signs Contracts with Mahindra Aeroscape, 3 others for Manufacturing of Aircraft Components

The latest contracts follow the allocation of the A320neo family cargo and bulk cargo doors manufacturing to Tata Advanced Systems earlier this year, Airbus said.

European aircraft and aerospace major Airbus on Monday said it has signed new contracts with multiple India-based suppliers for the manufacturing of components for commercial aircraft.

Contracts have been signed with Aequs, Dynamatic, Gardner and Mahindra Aerospace for the supply of airframe and wing parts across Airbus’ A320neo, A330neo and A350 programmes, the company said in a statement.

The latest contracts follow the allocation of the A320neo family cargo and bulk cargo doors manufacturing to Tata Advanced Systems earlier this year, Airbus said.

The company already procures components and services worth $750 million every year from India, and the latest round of contracts will add significantly to those volumes, it said.

“Make in India is at the core of Airbus’ strategy in India. We are proud that we are putting in place all the critical building blocks for an integrated industrial ecosystem that will propel India into the front ranks of aerospace manufacturing nations,” said Rémi Maillard, President and Managing Director of Airbus India and South Asia.

“For Airbus, India is not just a market but a strategic resource hub for both human capital and aerospace components and services. We are proud to extend our partnership with Aequs, Dynamatic, Gardner and Mahindra Aerospace,” he said.

These contracts will support the ramp-up of Airbus’ commercial aircraft programmes globally, while strengthening capability and capacity in the aviation ecosystem of India across multiple technologies, including sheet metal, machining and extrusion profiles, the company said.

Together with its supply chain, Airbus said, it supports nearly 10,000 jobs in India, which is expected to go up to 15,000 by 2025.

source/content: thehindu.com (headline edited)

INTERNATIONAL: DEFENCE / INDIAN AIR FORCE / MAKE IN INDIA : Airbus Defence & Space hands over First of the 56, C-295 Transport Aircraft to IAF at a ceremony in Spanish city of Seville. The 1st Make in India C-295 will roll out from Vadodara in 2026.

The final assembly line for the C295 aircraft in Vadodara is set to be operational in November next year.

Chief of Air Staff Air Chief Marshal VR Chaudhari on Wednesday received the first of the 56 C295 transport aircraft two years after India sealed a Rs 21,935-crore deal with Airbus Defence and Space to procure the jets to replace its ageing Avro–748 fleet.

Air Chief Marshal Chaudhari, receiving the aircraft at the aerospace major’s production facility in the southern Spanish city of Seville, described it as a “momentous day” for the IAF and India as 40 C-295 out of the total fleet will be manufactured in Vadodara.

“It is a momentous day for us, for the Indian Air Force in particular, and a nation as a whole to receive the first aircraft which marks the beginning of a new era, wherein we will be manufacturing 40 of these aircraft in India,” he said.

Under the deal, Airbus will deliver the first 16 aircraft in ‘fly-away’ condition from its final assembly line in Seville by 2025 and the subsequent 40 aircraft will be manufactured and assembled by Tata Advanced Systems (TASL) in India as part of an industrial partnership between the two companies.

“It gives a tremendous boost to the capability of moving our forces to the frontline when required,” Air Chief Marshal Chaudhari said.

The Chief of Air Staff also took a sortie on the new aircraft.

The C295, in transport configuration and with an indigenous electronic warfare suite, will leave Airbus’ production site in Seville for Delhi on September 15. It will be piloted by a joint IAF-Airbus crew.

“While the first aircraft was rolled out from Spain, the 17th aircraft will be assembled at the final assembly line in Baroda in 2026. It will mark a historic moment as the first time a military transport aircraft will be fully manufactured in India,” Air Chief Marshal Chaudhari told PTI.

The first ‘Make in India’ C295 will roll out of the Vadodara final assembly line in September 2026 in what will be a milestone for the Indian aerospace industry. The final aircraft is expected to be delivered to the IAF by August 2031.

“It was only two years ago that we signed this contract with India, the largest order in the history of the C295,” said Jean-Brice Dumont, Airbus’ Head of Military Air Systems.

“Today, we are enhancing the capabilities of the Indian Air Force and modernising its transport fleet by delivering the first aircraft on schedule. This is the beginning of an exciting and long-term journey with the Indian Air Force,” he said.

The production of components of these aircraft has already started in the Main Constituent Assembly (MCA) facility in Hyderabad, southern India. These parts will be shipped to the Final Assembly Line (FAL) in Vadodara which is expected to be operational by November 2024.

In October last year, Prime Minister Narendra Modi laid the foundation stone of the manufacturing facility for C295 planes in Vadodara. It will be the first military aircraft to be manufactured in India by a private consortium.

The Indian Air Force (IAF) is procuring the C295 aircraft to replace its fleet of ageing Avro-748 planes that entered the service over six decades back.

The global C295 programme comprises a total of 280 orders from 39 operators, making it an unmatched aircraft in its weight and mission class, the plane maker said.

The C295 is known to be a superior aircraft used for tactical transport of up to 71 troops or 50 paratroopers, and for logistic operations to locations that are not accessible to current heavier aircraft.

The aircraft can airdrop paratroops and loads, and also be used for casualty or medical evacuation.

The aircraft is capable of performing special missions as well as disaster response and maritime patrol duties.

After the mega deal was finalised last year, Airbus said the C295 programme will see the company bring its complete bouquet of world-class aircraft manufacturing and servicing to India in collaboration with its industrial partners.

In May, the first C295 aircraft built for India successfully completed its maiden flight in Seville. The second one is in the final assembly at the Seville facility and is scheduled to be delivered to the IAF in May next year.

Six pilots from the IAF and 20 technicians have already undergone extensive training at the Seville facility.

The final assembly line for the C295 aircraft in Vadodara is set to be operational in November next year.

Officials said the IAF will be the world’s largest operator of the C295.

Except for the headline, this story has not been edited by The Telegraph Online staff and has been published from a syndicated feed.

source/content: telegraphindia.com (headline edited)

INTERNATIONAL: MANUFACTURING /AUTOMOTIVE EXPORTS: Maruti Suzuki Commences Exports of compact SUV Fronx

Maruti Suzuki India said it had begun exports of the newly introduced compact SUV Fronx. The first batch of 556 vehicles was shipped from Mundra, Mumbai, and Pipavav Ports to destinations in Latin America, West Asia and Africa, the automaker said.

“The newly launched Fronx is an important model in our portfolio, and we are confident that it will augment our ambitious export plans,” said MD & CEO Hisashi Takeuchi.

“Aligned with the Government of India’s efforts towards Make in India, we are focussed to lead the export of cars manufactured in India. With support from our parent company, Suzuki Motor Corporation we have expanded our portfolio and are now exporting to more markets,” he said.