Tag Archives: Uttar Pradesh Records

NATIONAL: HEALTH & MEDICAL: RESEARCH: The Central Drug Research Institute (CDRI) in Lucknow, Develops Oral Pill to Cure Fractures

The Central Drug Research Institute (CDRI) in Lucknow has developed an oral pill that will help in healing fracture in lesser time.

The phase-1 clinical trials of CDRI-1,500 molecule will begin soon.

CDRI’s senior principal scientist Divya Singh, said, “As accident rate in India is among the highest in the world, which leads to significant morbidity and mortality, development of this medicine which gives quick relief, has no side-effects and can heal fractures at a faster rate is much needed.”

She further said, “CDRI is presently working on two novel bone healing entities CDRI-1500 and CDRI-399. We have received all the required approvals from drug regulatory bodies and are ready for the phase-1 clinical trial of CDRI-1500.”

The scientist said CDRI-1500 is a first-in-class orally active fracture healing synthetic molecule. Currently, there is no orally active fracture healing synthetic molecule available nationally or internationally.

So far BMP2 molecule has been approved for fractures suffered by children and adults by the Food and Drug Administration. However, the use of BMP2 is restricted as it leads to numerous clinical complications and involves a very high cost, she added.

On the other hand, CDRI-1500 will not only be safe and economical but intake of this tablet will provide a quicker relief from pain as it promotes the expression of genes involved in bone regeneration and repair.

The main advantage of CDRI-1500 is that even its low dose has been found to be effective in healing fractures, she said.

“In our experiments, we found that the molecule promoted fracture healing in Sprague Dawley rats and New Zealand white rabbits at a very low dose given orally to rats and rabbits. We have received an Indian and US patent for the CDRI 1500 molecule,” Divya Singh added.

source/content: bhaskarlive.in / IANS (headline edited)

NATIONAL: DISTRIBUTION & WAREHOUSING LOGISTICS:Boeing Opens Its First India-Focused Distribution Centre In Uttar Pradesh

The aerospace company asserted that the new site is part of its continued commitment to expanding its presence in the country and delivering an efficient, cost-effective and local solution.

Global aerospace major Boeing has opened its first India-focused distribution centre in Khurja, Uttar Pradesh. The 36,000-square-foot parts warehouse will support regional aviation customers in maximising fleet utilisation. 

The aerospace company, in a release issued on Monday, asserted that the new site is part of its continued commitment to expanding its presence in the country and delivering an efficient, cost-effective and local solution. 

“The Boeing India Distribution Center illustrates Boeing’s commitment to supporting the growth of this market, aligned with the government’s Aatmanirbhar Bharat vision. This centre will support the emergent needs of spare parts for Boeing aircraft in India, reducing lead times, improving availability and supporting the MRO industry here,” said Salil Gupte, president, of Boeing India. 

The new India location is one of eight distribution centres around the world. 

“The India Distribution Center represents another significant step forward in Boeing’s strategy to provide parts and services when and where customers need them,” said William Ampofo, vice president, Parts and Distribution Services and Supply Chain, Boeing Global Services. 

“It also represents our commitment to delivering efficient, cost-effective solutions for Boeing’s commercial airplane customers in the region.” 

The aerospace company announced its investment in the distribution centre less than a year ago during Aero India 2023 and the first parts were shipped to customers in December 2023. 

The India distribution centre is positioned strategically along India’s Eastern Freight Corridor, with proximity to both Delhi and the upcoming Jewar airport. The warehouse, which prioritises innovation, safety and sustainability, is operated in collaboration with third-party logistics provider DB Schenker. 

These initiatives encompass a partnership with GMR Aero Technic to establish a Boeing Converted Freighter line in Hyderabad and the establishment of a Global Support Center in Gurgaon. 

Additionally, Boeing has committed a USD 100 million investment in infrastructure and pilot training programs to support India’s growing demand for pilots in the coming two decades. (ANI) 

source/content: businessworld.in / BW Business World (headline edited)